Results 81 to 90 of about 777,793 (384)

Identificación molecular y actividad sobre sustratos cromogénicos de la venombina A del veneno de la serpiente peruana Bothrops atrox

open access: yesRevista Peruana de Biología, 2011
En el presente trabajo se ha realizado la identificación molecular de la enzima similar a trombina (EST) del veneno de Bothrops atrox y se ha evaluado su actividad enzimática sobre diversos sustratos sintéticos.
Gustavo A. Sandoval   +4 more
doaj   +1 more source

Effect of low cost mole drainage technology on yield of chickpea (Cicer arietinum L.) under waterlogged vertisols of Maharashtra, India [PDF]

open access: yes, 2016
The field experiment was conducted on performance of mole drainage under irrigated and waterlogged vertisols of Maharashtra at Agricultural Research Station, K. Digraj, Dist. Sangli (M.S.), India during 2009-10 to 2011 -12.
Kamble, B.M.   +2 more
core   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

O Magach ze Wschodu

open access: yesRuch Biblijny i Liturgiczny, 1949

Marian Molé
doaj   +1 more source

High molecular weight hyaluronan mediates the cancer resistance of the naked mole-rat

open access: yesNature, 2013
The naked mole rat (Heterocephalus glaber) displays exceptional longevity, with a maximum lifespan exceeding 30 years. This is the longest reported lifespan for a rodent species and is especially striking considering the small body mass of the naked mole
Xiao Tian   +9 more
semanticscholar   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

Les instituteurs romands et l’éducation nouvelle, entre enthousiasme et résistances (années 1920)

open access: yesSchweizerische Zeitschrift für Bildungswissenschaften, 2019
L’Institut Jean-Jacques Rousseau a joué un rôle majeur dans le développement de l’éducation nouvelle et des sciences de l’éducation en Suisse romande.
Frédéric Mole
doaj   +1 more source

Review: Claire Nally's Steampunk: Gender, Subculture and the Neo-Victorian. London: Bloomsbury Academic, 2019.

open access: yesC21 Literature: Journal of 21st-century Writings, 2021
In a world where ‘Victorian Values’ serve as an established trope to be satirised, but are also becoming frighteningly central to conservative political logics once more, Claire Nally’s Steampunk: Gender, Subculture & the Neo-Victorian offers a ...
Megen de Bruin-Molé
doaj   +2 more sources

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

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