Results 1 to 10 of about 279,147 (262)

Recent advances in molecular mechanisms to improve the efficacy of CAR-T cell therapy for viral diseases, cancer, and autoimmune diseases [PDF]

Stem Cell Research & Therapy
Chimeric antigen receptor (CAR)-T cell therapy has transformed the treatment of hematological malignancies, yet its broader application to solid tumors, chronic viral infections, and autoimmune diseases remains constrained by antigen heterogeneity ...
Hany E. Marei, Giacomo Pozzoli, Sara Caratelli, Carlo Cenciarelli   +3 more
doaj   +2 more sources

Antiproliferative effects of fresh water crab hemolymph and meat extract on breast cancer cell line [PDF]

Journal of Shahrekord University of Medical Sciences, 2021
Background and aims: Despite the advances in drugs, side effects of chemotherapy drugs continue to exist. Therefore, more attention has been paid to the compounds derived from medicinal herbs and aquatic organisms.
Leila Rezakhani, Morteza Alizadeh, Esmaeel Sharifi, Mostafa Soleimannejad, Akram Alizadeh   +4 more
doaj   +1 more source

Prominin‐1 expression in the testis/epididymis and fertility

Reproductive Medicine and Biology, 2023
The contribution of Prominin‐1 (aka CD133) to male fertility has recently been (re)investigated, with contradictory results. Early findings, essential for deciphering its role, have unfortunately been neglected.
Christine A. Fargeas, József Jászai, Denis Corbeil   +2 more
doaj   +1 more source

ETHICAL ISSUES IN CELLULAR AND MOLECULAR MEDICINE AND TISSUE ENGINEERING [PDF]

Journal of Cellular and Molecular Medicine, 2008
The objective of tissue engineering is to create or recreate living body parts or organs that will fully integrate with the recipient's body. The advent of tissue engineering as a new field of research with a high potential towards the clinical care of patients from bench to bedside has involved numerous different scientists in various fields of ...
Horch, Raymund E, Popescu, L M, Maio, Giovanni, Vacanti, Charles   +3 more
openaire   +4 more sources

Unveiling the secrets of marine—derived fucoidan for bone tissue engineering—A review

Frontiers in Bioengineering and Biotechnology, 2023
Biomedical uses for natural polysaccharides of marine origin are growing in popularity. The most prevalent polysaccharides, including alginates, agar, agarose and carrageenan, are found in seaweeds.
Anupama Devi V. K., Anupama Devi V. K., Anjaneyulu Udduttula, Amit Kumar Jaiswal   +3 more
doaj   +1 more source

Copper / cobalt doped strontium-bioactive glasses for bone tissue engineering applications

Open Ceramics, 2023
In this study, we synthesized and characterized the sol-gel derived strontium BGs (SrBG) based on the 58 S glass in which copper (Cu) (Cu-SrBGs) or cobalt (Co) (Co-SrBGs) ions were separately substituted with calcium (Ca).
Neda Alasvand, Sara Simorgh, Maziar Malekzadeh Kebria, Azam Bozorgi, Salah Moradi, Vahid Hosseinpour Sarmadi, Kaveh Ebrahimzadeh, Naser Amini, Farzad Kermani, Saeid Kargozar, Peiman Brouki Milan   +10 more
doaj   +1 more source

Polyrotaxanes as emerging biomaterials for tissue engineering applications: a brief review

Inflammation and Regeneration, 2020
The field of tissue engineering and regeneration constantly explores the possibility of utilizing various biomaterials’ properties to achieve effective and uneventful tissue repairs.
Arun Kumar Rajendan, Yoshinori Arisaka, Nobuhiko Yui, Sachiko Iseki   +3 more
doaj   +1 more source

Modeling early changes associated with cartilage trauma using human-cell-laden hydrogel cartilage models

Stem Cell Research & Therapy, 2022
Background Traumatic impacts to the articular joint surface are known to lead to cartilage degeneration, as in post-traumatic osteoarthritis (PTOA). Limited progress in the development of disease-modifying OA drugs (DMOADs) may be due to insufficient ...
Chunrong He, Karen L. Clark, Jian Tan, Hecheng Zhou, Rocky S. Tuan, Hang Lin, Song Wu, Peter G. Alexander   +7 more
doaj   +1 more source

Regional effect on the molecular clock rate of protein evolution in Eutherian and Metatherian genomes

BMC Ecology and Evolution, 2021
Background Different types of proteins diverge at vastly different rates. Moreover, the same type of protein has been observed to evolve with different rates in different phylogenetic lineages.
Raf Huttener, Lieven Thorrez, Thomas in‘t Veld, Barney Potter, Guy Baele, Mikaela Granvik, Leentje Van Lommel, Frans Schuit   +7 more
doaj   +1 more source

GC content of vertebrate exome landscapes reveal areas of accelerated protein evolution

BMC Evolutionary Biology, 2019
Background Rapid accumulation of vertebrate genome sequences render comparative genomics a powerful approach to study macro-evolutionary events. The assessment of phylogenic relationships between species routinely depends on the analysis of sequence ...
R. Huttener, L. Thorrez, T. in’t Veld, M. Granvik, L. Snoeck, L. Van Lommel, F. Schuit   +6 more
doaj   +1 more source