Results 191 to 200 of about 142,606 (227)

Baseline Neuroinflammation Stratifies TSPO‐PET Response to Disease‐Modifying Therapy in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch, Markus Matilainen, Giulia N. Baldrighi, Marjo Nylund, Maija Saraste, Laura Airas   +5 more
wiley   +1 more source

Phage-assisted evolution of allosteric protein switches. [PDF]

Nat Commun
Southern NT, von Bachmann A, Hovsepyan A, Griebl M, Wolf B, Lemmen N, Kroell AS, Westermann S, Mathony J, Niopek D.   +9 more
europepmc   +1 more source

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias, Federica Avantaggiato, Gianni Pezzoli, Andrea Canessa   +3 more
wiley   +1 more source

AI/ML-Assisted SERS Biosensing for Biomolecular Detection: From Direct Spectral Response to Integrated Diagnostic Systems. [PDF]

Biosensors (Basel)
Park JG, Park W, Choi S, Lee S, Kim M.
europepmc   +1 more source

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

Arthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source

Nanoparticle-Based Approaches for Enhancing In Vitro Fertilization in Animal Reproduction. [PDF]

Int J Mol Sci
Gałęska E, Kowalczyk A, Samardžija M, Gregurić Gračner G, Wrzecińska M, Araujo JP, Malagón JÁH, Camiña M, Czerniawska-Piątkowska E, Dobrzański Z.   +9 more
europepmc   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

GAPIT version 4: integration of GWAS into genomic prediction. [PDF]

Mol Biol Evol
Wang J, Zhang Z.
europepmc   +1 more source

Beyond target engagement: RNA therapeutics and the neuroimmune challenge in tauopathies. [PDF]

J Prev Alzheimers Dis
Breen EA.
europepmc   +1 more source

Advancing anthracnose resistance in dry beans through the transition from traditional to computational breeding efforts. [PDF]

Front Plant Sci
Patel A, Ahlawat S, Lorenc P, Vazin M, Maleki M, Yoosefzadeh Najafabadi M.   +5 more
europepmc   +1 more source