Results 1 to 10 of about 842,627 (287)

Prediction of the Presence of Targetable Molecular Alteration(s) with Clinico-Metabolic ¹⁸ F-FDG PET Radiomics in Non-Asian Lung Adenocarcinoma Patients [PDF]

Diagnostics, 2022
This study aimed to investigate if combining clinical characteristics with pre-therapeutic 18 F-fluorodeoxyglucose (18 F-FDG) positron emission tomography (PET) radiomics could predict the presence of molecular alteration(s) in key molecular targets in ...
Nicolas Aide, Kathleen Weyts, Charline Lasnon   +2 more
doaj   +2 more sources

Molecular alteration patterns predict tumor behavior in papillary thyroid carcinoma independent of tumor size: insights from an international multicenter retrospective study [PDF]

Thyroid Research
Background Molecular testing is a well-established tool that assists in the management of thyroid nodules and allows classification in distinct molecular alteration patterns: BRAF-like, RAS-like and non-BRAF-non-RAS (NBNR).
Grégoire B. Morand, Idit Tessler, Simon E. Thurnheer, Kayla E. Payne, Maxine Noik, Josh Krasner, Tzahi Yamin, Marc P. Pusztaszeri, Richard J. Payne, Galit Avior   +9 more
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Deciphering the Clinical Implications of Concurrent Chromosome 7 Gain and Chromosome 10 Loss in Glioblastoma: A Scoping Review [PDF]

Brain Sciences
Background/Objectives: Combined chromosome 7 gain and chromosome 10 loss (+7/−10) is the most frequent cytogenetic alteration and a defining diagnostic criterion for isocitrate dehydrogenase wild-type (IDHwt) glioblastoma.
Edgar G. Ordóñez-Rubiano, Alexandra Ramos-Márquez, Raul F. Vega-Alvear, Clara Ruiz-Forero, Antonia Cadavid-Cobo, Santiago Fuentes-Tapias, Pedro Andrade-Andrade, Alba L. Cómbita, César Payán-Gómez, Rafael Parra-Medina, Diego F. Gómez, Juan F. Ramón, Fernando Hakim   +12 more
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Integrated proteome, phospho-proteome and malonyl-proteome revealed a molecular alteration of breast cancer [PDF]

Scientific Reports
Breast cancer is a heterogeneous disease with a high incidence, but its proteomes have not yet been thoroughly characterized. To construct a comprehensive dynamic network of breast cancer-related proteins, we integrated the whole-cell proteome (WCP ...
Chenxu Guo, Mingliang Zhang, Xin Jin, Chao Zhu, Rui Xu, Jiahe Sun, Jun Qian   +6 more
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Clinical updates on gliomas and implications of the 5th edition of the WHO classification of central nervous system tumors

Frontiers in Oncology, 2023
BackgroundThe 5th edition of the World Health Organization (WHO) classification of central nervous system tumors incorporated specific molecular alterations into the categorization of gliomas.
Xiaopeng Guo, Xiaopeng Guo, Yixin Shi, Yixin Shi, Delin Liu, Delin Liu, Yilin Li, Yilin Li, Wenlin Chen, Yaning Wang, Yuekun Wang, Hao Xing, Yu Xia, Yu Xia, Junlin Li, Junlin Li, Jiaming Wu, Jiaming Wu, Tingyu Liang, Hai Wang, Qianshu Liu, Qianshu Liu, Shanmu Jin, Shanmu Jin, Tian Qu, Tian Qu, Siying Guo, Siying Guo, Huanzhang Li, Huanzhang Li, Tianrui Yang, Tianrui Yang, Kun Zhang, Kun Zhang, Yu Wang, Yu Wang, Wenbin Ma, Wenbin Ma   +37 more
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Histological and molecular glioblastoma, IDH-wildtype: a real-world landscape using the 2021 WHO classification of central nervous system tumors

Frontiers in Oncology, 2023
IntroductionGlioblastoma (GBM), the most lethal primary brain malignancy, is divided into histological (hist-GBM) and molecular (mol-GBM) subtypes according to the 2021 World Health Organization classification of central nervous system tumors. This study
Xiaopeng Guo, Xiaopeng Guo, Lingui Gu, Yilin Li, Yilin Li, Zhiyao Zheng, Zhiyao Zheng, Zhiyao Zheng, Wenlin Chen, Yaning Wang, Yuekun Wang, Hao Xing, Yixin Shi, Yixin Shi, Delin Liu, Delin Liu, Tianrui Yang, Tianrui Yang, Yu Xia, Yu Xia, Junlin Li, Junlin Li, Jiaming Wu, Jiaming Wu, Kun Zhang, Kun Zhang, Tingyu Liang, Hai Wang, Qianshu Liu, Qianshu Liu, Shanmu Jin, Shanmu Jin, Tian Qu, Tian Qu, Siying Guo, Siying Guo, Huanzhang Li, Huanzhang Li, Yu Wang, Yu Wang, Wenbin Ma, Wenbin Ma   +41 more
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Enhancing the Catalytic Performance of Candida antarctica Lipase B by Chemical Modification With Alkylated Betaine Ionic Liquids

Frontiers in Bioengineering and Biotechnology, 2022
Various betaine ionic liquids composed of different chain lengths and different anions were designed and synthesized to modify Candida antarctica lipase B (CALB).
Yu Xue, Xiao-Guang Zhang, Ze-Ping Lu, Chao Xu, Hua-Jin Xu, Yi Hu   +5 more
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Theileria infection in bullfighting cattle in Thailand [PDF]

Veterinary World, 2022
Background and Aim: An apicomplexan protozoan parasite, namely, Theileria, primarily causes theileriosis in cattle worldwide. The virulence of the disease has been neglected because of it's low pathogenicity.
Pirayu Rakwong, Narissara Keawchana, Ruttayaporn Ngasaman, Ketsarin Kamyingkird   +3 more
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Novel insight into histological and molecular astrocytoma, IDH‐mutant, Grade 4 by the updated WHO classification of central nervous system tumors

Cancer Medicine, 2023
Background The latest fifth edition of the World Health Organization (WHO) classification of the central nervous system (CNS) tumors (WHO CNS 5 classification) released in 2021 defined astrocytoma, IDH‐mutant, Grade 4.
Wenlin Chen, Siying Guo, Yaning Wang, Yixin Shi, Xiaopeng Guo, Delin Liu, Yilin Li, Yuekun Wang, Hao Xing, Yu Xia, Junlin Li, Jiaming Wu, Tingyu Liang, Hai Wang, Qianshu Liu, Shanmu Jin, Tian Qu, Huanzhang Li, Tianrui Yang, Kun Zhang, Yu Wang, Wenbin Ma   +21 more
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Are FGFR and IDH1-2 alterations a positive prognostic factor in intrahepatic cholangiocarcinoma? An unresolved issue

Frontiers in Oncology, 2023
Despite representing some of the most common and investigated molecular changes in intrahepatic cholangiocarcinoma (iCCA), the prognostic role of FGFR and IDH1/2 alterations still remains an open question. In this review we provide a critical analysis of
Giovanni Brandi, Giovanni Brandi, Chiara Deiana, Chiara Deiana, Linda Galvani, Linda Galvani, Andrea Palloni, Angela Dalia Ricci, Alessandro Rizzo, Simona Tavolari, Simona Tavolari   +10 more
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