Results 91 to 100 of about 842,627 (287)

Histopathological Alteration and Molecular Detection of Gills Rot Fungus in Carp Fish [PDF]

Journal of Applied Veterinary Sciences
Nowadays, diseases are a major concern in fish production, particularly in gills, which play a crucial role in blood oxygenation, acid-base balance, osmoregulation, and waste elimination.
Zahraa Al-Jumaa, Shahbaa AL-Taee, Mohammed Jaber, Aseel Rahhawi   +3 more
doaj   +1 more source

Nanoscale Infrared Imaging Analysis of Carbonaceous Chondrites to Understand Organic-Mineral Interactions During Aqueous Alteration [PDF]

, 2019
Organic matter in carbonaceous chondrites is distributed in fine-grained matrix. To understand pre- and postaccretion history of organic matter and its association with surrounding minerals, microscopic techniques are mandatory.
Baden, Naoki, Kebukawa, Yoko, Kobayashi, Hanae, Kobayashi, Kensei, Kondo, Masashi, Urayama, Norio, Zolensky, Michael E.   +6 more
core   +2 more sources

Molecular alterations contributing to pancreatic cancer chemoresistance [PDF]

Pancreatology, 2017
Pancreatic ductal adenocarcinoma (PDAC) is one of the most common causes of cancer-related death all over the world. This disease is difficult to treat and patients have an overall 5-year survival rate of less than 5%. Although two drugs, gemcitabine (GEM) and 5-fluorouracil (5-FU) have been shown to improve the survival rate of patients systematically,
Azam Rajabpour, Farzad Rajaei, Ladan Teimoori-Toolabi   +2 more
openaire   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Behavioral and Brain Gene and Protein Changes in Female Mice Consuming Ethanol During Pregnancy and Lactation

Biomolecules
Alcohol consumption during pregnancy and lactation remains a significant global issue. Preventive policies have proven insufficient, and consumption rates remain high, mainly due to a lack of awareness, the misconception that only high alcohol intake ...
Daniela Navarro, Francisco Navarrete, Nerina Villalba, Abraham B. Torregrosa, Laura Caltana, Ani Gasparyan, Alicia Brusco, Jorge Manzanares   +7 more
doaj   +1 more source

Electronic Control of Spin Alignment in pi-Conjugated Molecular Magnets

, 2003
Intramolecular spin alignment in pi-conjugated molecules is studied theoretically in a model of a Peierls-Hubbard chain coupled with two localized spins. By means of the exact diagonalization technique, we demonstrate that a spin singlet (S=0) to quartet
A. Rajca, A. A. Ovchinnikov, E. Wasserman, H. Iwamura, H. Mizouchi, H. Nishide, J. S. Miller, M. Matsushita, N. Mataga, O. Sato, Ping Huai, Shuji Abe, Yukihiro Shimoi   +12 more
core   +1 more source

The antibacterial action of microcin J25: evidence for disruption of cytoplasmic membrane energization in Salmonella newport [PDF]

, 2001
Microcin J25 (MccJ25) is a cyclic peptide of 21 unmodified amino acid residues produced by a fecal strain of Escherichia coli. It has previously been shown that the antibiotic activity of this peptide is mainly directed to Enterobacteriaceae, including ...
Farias, Ricardo Norberto, Fernandez, Beatriz Eugenia, Morero, Roberto Dionisio, Rintoul, Maria Regina, Salomon, Raul Armando   +4 more
core   +1 more source

Molecular Alterations of KIT Oncogene in Gliomas

Analytical Cellular Pathology, 2007
Gliomas are the most common and devastating primary brain tumours. Despite therapeutic advances, the majority of gliomas do not respond either to chemo or radiotherapy. KIT, a class III receptor tyrosine kinase (RTK), is frequently involved in tumourigenic processes. Currently, KIT constitutes an attractive therapeutic target.
Gomes, Ana L., Reis-Filho, Jorge S., Lopes, José M., Martinho, Olga, Lambros, Maryou B. K., Martins, Albino, Schmitt, Fernando, Pardal, Fernando, Reis, R. M.   +8 more
openaire   +4 more sources

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source