Results 271 to 280 of about 842,627 (287)
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Molecular alterations in metaplastic breast carcinoma
Journal of Clinical Pathology, 2013Metaplastic carcinoma of the breast is a rare and heterogeneous subtype of breast carcinoma with a generally poor outcome, and few therapeutic options once disease recurs or progresses. Metaplastic carcinomas of the breast are usually of a larger size at diagnosis, with less frequent nodal metastasis compared with invasive ductal carcinoma no special ...
Cooper, Caroline L. +5 more
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Targetable molecular alterations in congenital glioblastoma
Journal of Neuro-Oncology, 2019Congenital glioblastomas (cGBMs) are uncommon tumors presenting in early infancy, variably defined as diagnosed at birth or at age less than 3 months by strict criteria, or more loosely, as occurring in very young children less than 12 months of age. Previous studies have shown that cGBMs are histologically indistinguishable from GBMs in older children
Ahmed Gilani +9 more
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Molecular alterations of interferons.
Texas reports on biology and medicine, 1978Interferons can be chemically and enzymatically altered to obtain molecular forms which differ in size, charge, and/or host-range from native interferons. These data suggest that small active cores of interferons can be obtained which may possess more desirable characteristics than native interferons, such as lack of "species-specificity"" and ...
W E, Stewart +3 more
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Altered Molecular Mechanisms of Diabetic Foot Ulcers
The International Journal of Lower Extremity Wounds, 2009The continuously increasing worldwide prevalence of diabetes will be accompanied by a greater incidence of diabetic foot ulcer, a complication in which many of the morphological processes involved in normal wound healing are disrupted. The highly complex and integrated process of wound healing is regulated by a large array of molecular factors.
Robert, Blakytny, Edward B, Jude
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Molecular cytogenetic characterization of cancer cell alterations
Cancer Genetics and Cytogenetics, 1997Chromosomal abnormalities are the hallmark of cancer cells. Recurring and highly consistent structural and numerical alterations have been identified in a large number of leukemias, lymphomas, and solid tumors. The identification of recurrent genetic alterations and the isolation of molecular markers have clinical applications in the diagnosis and ...
N C, Popescu, D B, Zimonjic
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Molecular alterations in chronic pancreatitis
Journal of Hepato-Biliary-Pancreatic Surgery, 2002Hany, Kayed +5 more
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Molecular Alterations in Musculoskeletal Lesions
2019The marriage of molecular genetics and soft tissue tumor pathology certainly represents one of the most fruitful events of the last decade. The close relationship between morphology (including immunohistochemistry) and molecular genetics was certified by the 2002 WHO classifications of bone and soft tissue tumors and further expended in the 2013 update.
Marta Sbaraglia +3 more
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Molecular alteration of gastric carcinoma.
Minerva gastroenterologica e dietologica, 2002Gastric cancer is constituted by two histomorphological entities ''intestinal'' and ''diffuse'' that differ in epidemiology, pathogenesis, clinical outcome and genetic profile. Two distinct molecular pathways of genomic destabilization have been identified in gastric carcinogenesis: the microsatellite mutator phenotype (MMP) and a phenotype associated ...
NARDONE, GERARDO ANTONIO PIO +2 more
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Molecular Alterations in Breast Cancer
1999Although not obligatory, many breast cancers appear to develop through a series of premalignant stages histologically defined as atypical hyperplasia and carcinoma in situ leading to invasive cancer (1,2). Accompanying this histologic progression are numerous molecular alterations that result in oncogene activation and/or tumor suppressor inactivation (
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[Molecular alterations in esophageal cancer].
Nihon Geka Gakkai zasshi, 2002The clinicopathological characteristics of esophageal cancer have gradually been clarified using molecular biologic methods developed over the past 20 years. For example, amplification of the c-erb B gene is a prognostic factor and predictive of lymph node involvement, while the amplification of the cyclin D1 gene is also a prognostic factor and ...
Soji, Ozawa +2 more
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