Anomalous pressure behavior of tangential modes in single-wall carbon nanotubes
, 2007 Using the molecular dynamics simulations and the force constant model we have studied the Raman-active tangential modes (TMs) of a (10, 0) single-wall carbon nanotube (SWNT) under hydrostatic pressure.
Bo Wang +6 more
core +1 more source
Landscape of targeted therapies for advanced urothelial carcinoma
Exploration of Targeted Anti-tumor TherapyBladder cancer (BC) is the tenth most common malignancy globally. Urothelial carcinoma (UC) is a major type of BC, and advanced UC (aUC) is associated with poor clinical outcomes and limited survival rates.
Shihao Shang +10 more
doaj +1 more source
Multi-determinants analysis of molecular alterations for predicting clinical benefit to EGFR-targeted monoclonal antibodies in colorectal cancer. [PDF]
PLoS ONE, 2009 KRAS mutations occur in 35-45% of metastatic colorectal cancers (mCRC) and preclude responsiveness to EGFR-targeted therapy with cetuximab or panitumumab.
Andrea Sartore-Bianchi +14 more
doaj +1 more source
Impact of template backbone heterogeneity on RNA polymerase II transcription. [PDF]
, 2014 Variations in the sugar component (ribose or deoxyribose) and the nature of the phosphodiester linkage (3'-5' or 2'-5' orientation) have been a challenge for genetic information transfer from the very beginning of evolution.
Chong, Jenny +5 more
core +1 more source
Frontiers in OncologyIntroductionAccurate identification and characterization of Large Genomic Rearrangements (LGR), especially duplications, are crucial for precise diagnosis and risk assessment. In this report, we characterized an intragenic duplication breakpoint of PALB2
Iulian O. Ban +11 more
doaj +1 more source
Molecular estimation of alteration in intestinal microbial composition in Hashimoto's thyroiditis patients [PDF]
, 2017 The gut microbiota has a crucial effect on human health and physiology. Hypothyroid Hashimoto’s thyroiditis (HT) is an autoimmune disorder manifested with environmental and genetic factors.
Guo, Hui +9 more
core +2 more sources
Penile Carcinoma: Risk Factors and Molecular Alterations [PDF]
The Scientific World JOURNAL, 2011 Penile carcinoma is a rare, male cancer. Although the incidence of penile carcinoma is very low in Western countries, in some countries, the incidence is significantly greater, with penile carcinoma accounting for ≤10% of all male malignancies. Greater insight has been gained in recent years as to its pathogenesis, the risk factors associated with its ...
Calmon, Marilia F. +3 more
openaire +5 more sources
Chromatic alteration on marble surfaces analysed by molecular biology tools
Conservation Science in Cultural Heritage, 2007 The patina represents a superficial natural alteration of the constituting matter of the work of art. It emerges from the natural and usual stabilization process that the materials of the surface undergo because of the interaction with outdoor agents ...
Franco Palla, Elena Tartamella
doaj +1 more source
The ribosomal protein RACK1 is required for microRNA function in both C. elegans and humans [PDF]
, 2011 Despite the importance of microRNAs (miRNAs) in gene regulation, it is unclear how the miRNA-Argonaute complex-or miRNA-induced silencing complex (miRISC)-can regulate the translation of their targets in such diverse ways.
Bajan, Sarah +7 more
core +3 more sources
Molecular Alterations in Dog Pheochromocytomas and Paragangliomas [PDF]
Cancers, 2019 Recently, genetic alterations in the genes encoding succinate dehydrogenase subunit B and D (SDHB and SDHD) were identified in pet dogs that presented with spontaneously arising pheochromocytomas (PCC) and paragangliomas (PGL; together PPGL), suggesting dogs might be an interesting comparative model for the study of human PPGL.
Esther Korpershoek +14 more
openaire +7 more sources