Results 101 to 110 of about 7,530,679 (394)
Empowering statistical methods for cellular and molecular biologists. [PDF]
, 2019 We provide guidelines for using statistical methods to analyze the types of experiments reported in cellular and molecular biology journals such as Molecular Biology of the Cell.
Pollard, Daniel A +2 more
core
The Two Regime method for optimizing stochastic reaction-diffusion simulations [PDF]
, 2011 The computer simulation of stochastic reaction-diffusion processes in biology is often done using either compartment-based (spatially discretized) simulations or molecular-based (Brownian dynamics) approaches. Compartment-based approaches can yield quick
Chapman, S. J., Erban, R., Flegg, M. B.
core +1 more source
Water is an active matrix of life for cell and molecular biology
Proceedings of the National Academy of Sciences of the United States of America, 2017 Szent-Győrgi called water the “matrix of life” and claimed that there was no life without it. This statement is true, as far as we know, on our planet, but it is not clear whether it must hold throughout the cosmos.
P. Ball
semanticscholar +1 more source
FEBS Letters, EarlyView.Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung +6 more
wiley +1 more source
Energy flow in biological system: Bioenergy transduction of V1-ATPase molecular rotary motor from E. hirae [PDF]
Progress in Biophysics and Molecular Biology 130, Part A, 33-38
(2017), 2017 We classify research fields in biology into those on flows of materials, energy, and information. As a representative energy transducing machinery in biology, our research target, V1-ATPase from a bacterium Enterococcus hirae, a typical molecular rotary motor is introduced.
arxiv
Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases
FEBS Letters, EarlyView.The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher +6 more
wiley +1 more source
arXiv, 1994 We will review some of the theoretical progresses that have been in the study of complex systems in physics and of their applications to biology.
arxiv
Live Cell Imaging Unveils Multiple Domain Requirements for In Vivo Dimerization of the Glucocorticoid Receptor [PDF]
, 2014 Glucocorticoids are essential for life, but are also implicated in disease pathogenesis and may produce unwanted effects when given in high doses.
Alvarez, Lautaro Damian +14 more
core +3 more sources
FEBS Letters, EarlyView.We present the first solution structure of the Ca2+‐depleted LETM1 F‐EF‐hand through a D676A/N678A Ca2+ binding‐deficient mutant, revealing a closed hydrophobic cleft caused by a unique F1‐helix pivot. The apo LETM1 F‐EF‐hand exhibits regiospecific hot and cold unfolding, sensitivity to physiological pH changes and potential for promiscuous heterotypic
Qi‐Tong Lin +2 more
wiley +1 more source
Giulio Fermi's contributions to biophysics and molecular biology [PDF]
arXiv, 2018 This paper presents a comprehensive list of the scientific articles of Giulio Fermi (1936-1997), son of the Italian-American physicist Enrico Fermi, published between 1962 and 1997. The initial research activity of Giulio was concerned with virology and biological cybernetics while, from 1975 onward, his work was completely devoted to protein ...
arxiv