Results 81 to 90 of about 398,640 (265)

Protocol for preparing monosodium urate crystals for in vitro and in vivo studies in mouse and human cells

open access: yesSTAR Protocols
Summary: Gout is caused by the deposition of monosodium urate crystals (MSUc) in the joints, triggering a unique inflammatory and metabolic response in macrophages.
Mohnish Alishala   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Special Issue “Molecular Biology in Forensic Science: Past, Present and Future”

open access: yes
Molecular biology has always represented an enviable tool in the fields of biosciences, diagnostics, and forensic sciences [...
Monica Salerno, Francesco Sessa
core   +1 more source

Systems biology of cell behavior

open access: yes, 2020
Systems Biology approaches to drug discovery largely focus on the increasing understanding of intracellular and cellular circuits, by computational representation of a molecular system followed by parameter validation against experimental data.
Umezawa Y.   +4 more
core  

Circ-CIMIRC inhibition alleviates CIH-induced myocardial damage via FbxL4-mediated ubiquitination of PINK1

open access: yesiScience
Summary: Obstructive sleep apnea (OSA) is a common sleep disordered breathing diseases that characterized by chronic intermittent hypoxia (CIH). This work aimed to explore the role of circ-CIMIRC in CIH-induced myocardial injury.
Runhua Wu   +6 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Molecular Biology: Challenges and Opportunities

open access: yes
“Latest Review Papers in Molecular Biology 2024”, a Special Issue of Current Issues in Molecular Biology (CIMB) that I have had the privilege of editing, called for articles on the challenges and opportunities in the field of molecular biology [...
Madhav Bhatia
core   +1 more source

Whither Molecular Biology? [PDF]

open access: yes, 1977
As has been the case with nuclear science, questions of molecular biology have become issues of public policy.
Sinsheimer, Robert L.
core  

International plant molecular biology: a bright future for green science

open access: yes, 2012
Sibum Sung, Enamul Huq and Z Jeffrey Chen* Author Affiliations Section of Molecular Cell and Developmental Biology, Center for Computational Biology and Bioinformatics, and Institute for Cellular and Molecular Biology, The University of Texas at ...
Sung, Sibum   +2 more
core   +1 more source

The molecular biology of arteriviruses.

open access: yesJournal of General Virology, 1998
.The establishment of an arterivirus family acknowledgesthemanyuniquebiologicalandmolecularpropertiesofitsfourpresent members. On the other hand, the affiliation with thecoronavirusesrecognizesanintriguingancestralrelationshipatthelevelofgenomeorganizationandreplication.ThegenomesequencesofEAV,PRRSV,LDVandSHFVwereinstrumentalin uniting and reclassifying ...
Snijder, E.J., Meulenberg, J.J.
openaire   +3 more sources

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