Results 101 to 110 of about 2,246,680 (313)
On microRNA and the Need for Exploratory Experimentation in Post-Genomic Molecular Biology [PDF]
, 2007 This paper is devoted to an examination of the discovery, characterization, and analysis of the functions of microRNAs, which also serves as a vehicle for demonstrating the importance of exploratory experimentation in current (post-genomic) molecular ...
Burian, Richard M., Richard M. Burian
core
An update on molecular biology of thyroid cancers [PDF]
, 2014 Differentiated thyroid cancer (DTC) is the most common endocrinological malignancy. There are several histological variants such as papillary and follicular thyroid carcinoma.
Baran, Yusuf, Ömür, Özgür
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Molecular Study of Sudden Cardiac Death [PDF]
The aim of the Special Issue “Molecular study of sudden cardiac death” was to gather new studies on the molecular biology of cardiac death, from both a fundamental and clinical perspective [...
Sorin Hostiuc
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Bioinformatic approaches for the structure and function of membrane proteins [PDF]
, 2019 Membrane proteins play important roles in the biology of the cell, including intercellular communication and molecular transport. Their well-established importance notwithstanding, the high-resolution structures; of membrane proteins remain elusive due ...
Nam, HJ, Kim, S, Jeon, J
core +1 more source
HMMR/RHAMM recruits SACK1D/FAM83D-CK1α complex at the mitotic spindle to control spindle alignment
iScienceSummary: The SACK1D/FAM83D-CK1α complex assembles at the mitotic spindle to orchestrate proper spindle positioning and error-free progression through mitosis.
Tyrell N. Cartwright +7 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Evolutionary cell biology: Functional insight from “Endless forms most beautiful” [PDF]
, 2015 In animal and fungal model organisms, the complexities of cell biology have been analyzed in exquisite detail and much is known about how these organisms function at the cellular level.
Richardson, Elizabeth +4 more
core +1 more source
iScienceSummary: In vitro models of scarring and fibrosis are essential to improve our understanding of disease mechanisms and ultimately develop much-needed therapeutic strategies.
Amy Lock +5 more
doaj +1 more source