Results 91 to 100 of about 7,134,993 (310)

Cell and Molecular Biology of Thyroid Disorders 2.0

open access: yes, 2021
This issue is the second volume of the previous Special Issue, “Cell and Molecular Biology of Thyroid Disorders” [...
Daniela Grimm
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Molecular Biology of the Gene

open access: yes, 2008
Though completely up-to-date with the latest research advances, the Sixth Edition of James D. Watson's classic book, Molecular Biology of the Gene retains the distinctive character of earlier editions that has made it the most widely used book in ...
Gann, A.   +5 more
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

09091 Executive Summary – Formal Methods in Molecular Biology [PDF]

open access: yes, 2009
Formal logical models play an increasing role in the newly emerging field of Systems Biology. Compared to the classical, well-established approach of modeling biological processes using continuous and stochastic differential equations, formal logical ...
Heiner, Monika   +3 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Molecular Study of Sudden Cardiac Death

open access: yes
The aim of the Special Issue “Molecular study of sudden cardiac death” was to gather new studies on the molecular biology of cardiac death, from both a fundamental and clinical perspective [...
Sorin Hostiuc
core   +1 more source

Open source bioimage informatics for cell biology [PDF]

open access: yes, 2009
Significant technical advances in imaging, molecular biology and genomics have fueled a revolution in cell biology, in that the molecular and structural processes of the cell are now visualized and measured routinely.
Eliceiri, Kevin W.   +1 more
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

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