Results 61 to 70 of about 3,481,947 (302)
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
FEBS Letters, EarlyView.Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Inhibiting ANP32E protects against acute kidney injury by regulating autophagy via the AMPK pathway
iScienceSummary: Ischemia-reperfusion (I/R) injury is a secondary injury that frequently occurs during acute kidney injury (AKI) treatment. Acidic nuclear phosphoprotein 32 family member E (ANP32E) disorders are associated with several pathological conditions ...
Chunjie Wang +4 more
doaj +1 more source
The EM Algorithm and the Rise of Computational Biology [PDF]
, 2010 In the past decade computational biology has grown from a cottage industry with a handful of researchers to an attractive interdisciplinary field, catching the attention and imagination of many quantitatively-minded scientists.
Citable Link +3 more
core +3 more sources
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Dual specificity kinase DYRK3 regulates cell migration by influencing the stability of protrusions
iScienceSummary: Plasma membrane-associated platforms (PMAPs) form at specific sites of plasma membrane by scaffolds including ERC1 and Liprin-α1. We identify a mechanism regulating PMAPs assembly, with consequences on motility/invasion. Silencing Ser/Thr kinase
Martina Ramella +8 more
doaj +1 more source
Systems biology in animal sciences [PDF]
, 2011 Systems biology is a rapidly expanding field of research and is applied in a number of biological disciplines. In animal sciences, omics approaches are increasingly used, yielding vast amounts of data, but systems biology approaches to extract ...
Bannink, A. +4 more
core +3 more sources
Switching from Prokaryotic Molecular Biology to Eukaryotic Molecular Biology [PDF]
Journal of Biological Chemistry, 2009 In the history of biology, the early 1950s to the mid-1960s represent a period of landmark discoveries that led to the establishment of a new science named Molecular Biology. The discovery of the double helical structure of DNA by Watson and Crick in 1953 facilitated the formulation of specific questions related to the hottest questions of the time ...
openaire +2 more sources
This Is Not a Myeloproliferative Neoplasm…
Pediatric Blood &Cancer, EarlyView.
Stephanie Juané Kennedy
wiley +1 more source