Integrated structural biology of the native malarial translation machinery and its inhibition by an antimalarial drug [PDF]
Our understanding of cellular events is hampered by the gap between the resolution at which we can observe events inside cells and our ability to replicate physiological conditions in test tubes.
Lee, Carolyn L +31 more
core +2 more sources
ABSTRACT Background Survival after relapse in pediatric acute myeloid leukemia (AML) remains poor, highlighting the critical importance of identifying prognostic factors to guide optimal relapse management. Methods We investigated the prognostic impact of multiparameter flow cytometry (MFC) measurable residual disease (MRD) in 188 patients with first ...
Camilla Poulsen +21 more
wiley +1 more source
Special Issue “Molecular Biology in Forensic Science: Past, Present and Future” [PDF]
Molecular biology has always represented an enviable tool in the fields of biosciences, diagnostics, and forensic sciences [...
Monica Salerno, Francesco Sessa
core +1 more source
Systems biology of cell behavior [PDF]
Systems Biology approaches to drug discovery largely focus on the increasing understanding of intracellular and cellular circuits, by computational representation of a molecular system followed by parameter validation against experimental data.
Umezawa Y. +4 more
core
Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan +18 more
wiley +1 more source
International plant molecular biology: a bright future for green science [PDF]
Sibum Sung, Enamul Huq and Z Jeffrey Chen* Author Affiliations Section of Molecular Cell and Developmental Biology, Center for Computational Biology and Bioinformatics, and Institute for Cellular and Molecular Biology, The University of Texas at ...
Sung, Sibum +2 more
core +2 more sources
Intracellular TMEM16A is necessary for myogenesis of skeletal muscle
Summary: Transmembrane protein 16A (TMEM16A) localizes at plasma membrane and controls chloride influx in various type of cells. We here showed an intracellular localization pattern of TMEM16A molecules.
Wen Yuan +14 more
doaj +1 more source
Impact of Metastatic Patterns on Survival and Response to Therapy in Neuroblastoma
ABSTRACT Background While the presence of metastases in neuroblastoma (NB) is a well‐established prognostic factor, the clinical significance of dissemination patterns and tumour burden and their impact on response and survival remains poorly understood.
Mariona Morell‐Daniel +15 more
wiley +1 more source
The influence of phosphoinositide lipids in the molecular biology of membrane proteins: recent insights from simulations [PDF]
The phosphoinositide family of membrane lipids play diverse and critical roles in eukaryotic molecular biology. Much of this biological activity derives from interactions of phosphoinositide lipids with integral and peripheral membrane proteins, leading ...
Yen, Hsin-Yung, Hedger, George
core +1 more source
A Richer and More Diverse Future for Cell Biology [PDF]
Our vision: within the next few decades the composition of the faculty of cell biology, and of all biological science departments, will reflect the diverse composition of the graduate students in those departments.
Virginia Valian +14 more
core +2 more sources

