Results 31 to 40 of about 7,134,993 (310)

Dot6/Tod6 degradation fine-tunes the repression of ribosome biogenesis under nutrient-limited conditions

open access: yesiScience, 2022
Summary: Ribosome biogenesis (Ribi) is a complex and energy-consuming process, and should therefore be repressed under nutrient-limited conditions to minimize unnecessary cellular energy consumption. In yeast, the transcriptional repressors Dot6 and Tod6
Kino Kusama   +7 more
doaj   +1 more source

The Molecular Biology Notebook on CD-ROM - a step toward the virtual laboratory

open access: yes, 1999
The Molecular Biology Notebook is a teaching tool for molecular biology, developed at the Institute of Arable Crops Research, Rothamsted, in association with local schools and the University of Luton.
Castells-Brooke, N. I. D.   +9 more
core   +1 more source

Molecular Radiation Biology

open access: yes, 2023
Abstract Various exogeneous and endogenous factors constantly cause damages in the biomolecules within a cell. For example, per day, 10,000–100,000 molecular lesions occur in DNA per cell. The molecule modifications that are formed disturb the structure and function of the affected molecules.
Reindl, Judith   +39 more
openaire   +2 more sources

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Intracellular lactate dynamics in Drosophila neurons

open access: yesiScience
Summary: Rates of lactate production and consumption reflect the metabolic state of many cell types, including neurons. Here, we investigated the effects of nutrient deprivation on lactate dynamics in Drosophila neurons by leveraging the limiting effects
Matthew S. Price   +5 more
doaj   +1 more source

Evaluation of colloidal platinum on cytotoxicity, oxidative stress and barrier permeability across the gut epithelium

open access: yesHeliyon, 2019
Colloidal platinum (Pt) is widely consumed due to its health promoting benefits. However, the exact biological effects of these nanoparticles have not been studied in detail, particularly in the gut. In the present study we observed that colloidal Pt was
Sinem Tunçer   +5 more
doaj   +1 more source

Intracellular TMEM16A is necessary for myogenesis of skeletal muscle

open access: yesiScience, 2022
Summary: Transmembrane protein 16A (TMEM16A) localizes at plasma membrane and controls chloride influx in various type of cells. We here showed an intracellular localization pattern of TMEM16A molecules.
Wen Yuan   +14 more
doaj   +1 more source

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan   +18 more
wiley   +1 more source

The Philosophy of Molecular and Developmental Biology [PDF]

open access: yes, 2000
Philosophical discussion of molecular and developmental biology began in the late 1960s with the use of genetics as a test case for models of theory reduction.
Griffiths, Paul Edmund
core  

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider   +15 more
wiley   +1 more source

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