Results 11 to 20 of about 398,640 (265)

Independent transcriptomic and proteomic regulation by type I and II protein arginine methyltransferases

iScience, 2021
Summary: Protein arginine methyltransferases (PRMTs) catalyze the post-translational monomethylation (Rme1), asymmetric (Rme2a), or symmetric (Rme2s) dimethylation of arginine. To determine the cellular consequences of type I (Rme2a) and II (Rme2s) PRMTs,
Maxim I. Maron, Stephanie M. Lehman, Sitaram Gayatri, Joseph D. DeAngelo, Subray Hegde, Benjamin M. Lorton, Yan Sun, Dina L. Bai, Simone Sidoli, Varun Gupta, Matthew R. Marunde, James R. Bone, Zu-Wen Sun, Mark T. Bedford, Jeffrey Shabanowitz, Hongshan Chen, Donald F. Hunt, David Shechter   +17 more
doaj   +1 more source

Correction: Ten simple rules for leveraging virtual interaction to build higher-level learning into bioinformatics short courses.

PLoS Computational Biology, 2023
[This corrects the article DOI: 10.1371/journal.pcbi.1010220.].
Wendi Bacon, Alexandra Holinski, Marina Pujol, Meredith Wilmott, Sarah L Morgan, European Molecular Biology Laboratory—European Bioinformatics Institute Training Team   +5 more
doaj   +1 more source

Premise and peril of Wnt signaling activation through GSK-3β inhibition

iScience, 2022
Summary: Wnt signaling pathways have been extensively studied in the context of several diseases, including cancer, coronary artery disease, and age-related disorders.
Samuel M. Law, Jie J. Zheng
doaj   +1 more source

A Molecular Biology Database Digest [PDF]

, 2000
Computational Biology or Bioinformatics has been defined as the application of mathematical and Computer Science methods to solving problems in Molecular Biology that require large scale data, computation, and analysis [18].
Kröger, Peer, Peer Kröger, Bry, François, François Bry   +3 more
core   +1 more source

Bone and Cartilage Biology

, 2023
Recent technical and conceptual advances in molecular and cellular biology have dramatically advanced bone and cartilage biology [...
Riko Nishimura
core   +1 more source

Cytoplasmic and mitochondrial aminoacyl-tRNA synthetases differentially regulate lifespan in Caenorhabditis elegans

iScience, 2022
Summary: Reducing the rate of translation promotes longevity in multiple organisms, representing a conserved mechanism for lifespan extension. Aminoacyl-tRNA synthetases (ARSs) catalyze the loading of amino acids to their cognate tRNAs, thereby playing ...
Tianlin Zheng, Qiang Luo, Chengxuan Han, Jiejun Zhou, Jianke Gong, Lei Chun, X.Z. Shawn Xu, Jianfeng Liu   +7 more
doaj   +1 more source

RPRM negatively regulates ATM levels through its nuclear translocation on irradiation mediated by CDK4/6 and IPO11

iScience, 2022
Summary: How the ataxia telangiectasia mutated (ATM) protein kinase, a core protein in DNA damage response, is regulated at post-transcription level remains unclear.
Yarui Zhang, Guomin Ou, Zhujing Ye, Zhou Zhou, Qianlin Cao, Mengting Li, Jingdong Wang, Jianping Cao, Hongying Yang   +8 more
doaj   +1 more source

Phosphate-induced activation of VEGFR2 leads to caspase-9-mediated apoptosis of hypertrophic chondrocytes

iScience, 2023
Summary: Low circulating phosphate (Pi) leads to rickets, characterized by expansion of the hypertrophic chondrocytes (HCs) in the growth plate due to impaired HC apoptosis.
Prem Swaroop Yadav, Garyfallia Papaioannou, Margaret M. Kobelski, Marie B. Demay   +3 more
doaj   +1 more source

Protocol for generating mutant zebrafish using CRISPR-Cas9 followed by quantitative evaluation of vascular formation

STAR Protocols, 2023
Summary: The use of vascular-specific transgenic zebrafish provides advantages for identifying new mutations affecting angiogenesis and vascular development.
Juanjuan Luo, Chunjiao Lu, Maya Wang, Xiaojun Yang   +3 more
doaj   +1 more source

Molecular biology of hearing

Laryngo- rhino- otologie, 2011
GMS Current Topics in Otorhinolaryngology - Head and Neck Surgery; 10:Doc06; ISSN 1865 ...
Stöver, Timo, Diensthuber, Marc
openaire   +5 more sources