Results 21 to 30 of about 3,481,947 (302)
Regulatory Molecular Biology [PDF]
Cell Cycle, 2006 Close regulations of molecular biological processes are essential for life. Defective controls cause diseases such as cancer and neurological malfunctions. We now are provided with a plethora of regulatory mechanisms exerted at many levels. Prominent are covalent protein modifications, non-covalent feedback inhibition that modifies enzyme activity, and
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Dark side illuminated: imaging of Toxoplasma gondii through the decades. [PDF]
, 2013 In the more than 100 years since its discovery, our knowledge of Toxoplasma biology has improved enormously. The evolution of molecular biology, immunology and genomics has had profound influences on our understanding of this ubiquitous bug.
McGovern, Kathryn E, Wilson, Emma H
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iScience, 2023 Summary: Low circulating phosphate (Pi) leads to rickets, characterized by expansion of the hypertrophic chondrocytes (HCs) in the growth plate due to impaired HC apoptosis.
Prem Swaroop Yadav +3 more
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STAR Protocols, 2023 Summary: The use of vascular-specific transgenic zebrafish provides advantages for identifying new mutations affecting angiogenesis and vascular development.
Juanjuan Luo +3 more
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The endocytosis of oxidized LDL via the activation of the angiotensin II type 1 receptor
iScience, 2021 Summary: Arrestin-dependent activation of a G-protein-coupled receptor (GPCR) triggers endocytotic internalization of the receptor complex. We analyzed the interaction between the pattern recognition receptor (PRR) lectin-like oxidized low-density ...
Toshimasa Takahashi +23 more
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miR-29cb2 promotes angiogenesis and osteogenesis by inhibiting HIF-3α in bone
iScience, 2022 Summary: Coordination between osteogenesis and angiogenesis is required for bone homeostasis. Here, we show that miR-29cb2 is a bone-specific miRNA and plays critical roles on angiogenesis-osteogenesis coupling during bone remodeling.
Liping Ouyang +12 more
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Rhabdomyosarcoma: Advances in Molecular and Cellular Biology. [PDF]
, 2015 Rhabdomyosarcoma (RMS) is the most common soft tissue malignancy in childhood and adolescence. The two major histological subtypes of RMS are alveolar RMS, driven by the fusion protein PAX3-FKHR or PAX7-FKHR, and embryonic RMS, which is usually ...
Duan, Zhenfeng +5 more
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mTORC2 regulates auditory hair cell structure and function
iScience, 2023 Summary: mTOR broadly controls cell growth, but little is known about the role of mTOR complex 2 (mTORC2) in the inner ear. To investigate the role of mTORC2 in sensory hair cells (HCs), we generated HC-specific Rictor knockout (HC-RicKO) mice.
Maurizio Cortada +3 more
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Developing Predictive Molecular Maps of Human Disease through Community-based Modeling [PDF]
, 2011 The failure of biology to identify the molecular causes of disease has led to disappointment in the rate of development of new medicines. By combining the power of community-based modeling with broad access to large datasets on a platform that promotes ...
Christine Suver +10 more
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Molecular biology of hearing [PDF]
Laryngo- rhino- otologie, 2011 GMS Current Topics in Otorhinolaryngology - Head and Neck Surgery; 10:Doc06; ISSN 1865 ...
Stöver, Timo, Diensthuber, Marc
openaire +5 more sources