Results 31 to 40 of about 3,853,576 (297)

Highly pathogenic porcine reproductive and respiratory syndrome virus nonstructural protein 1 interacts with TRAF6 to activate the TAK1/p38/JNK/AP-1 signaling and induce IL-1β

Journal of Virology
Porcine reproductive and respiratory syndrome (PRRS) caused by PRRS virus (PRRSV) is a highly contagious disease that severely threatens the global pig industry. A significant symptom of PRRS is severe pneumonia. At present, studies have shown that IL-1β
Jiaying Zhu, Shuyuan Guo, Ailing Liang, Chang Liu, Hao Zhou, Zhongzhou Chen, Wen-hai Feng   +6 more
doaj   +1 more source

Comprehensive Analysis of GASA Family Members in the Peanut Genome: Identification, Characterization, and Their Expressions in Response to Pod Development

Agronomy, 2022
The gibberellic acid-stimulated Arabidopsis (GASA) gene family is essential for plant growth and development, hormone level control, and phytohormone signal transmission. Different plants have been shown to contain numerous GASA homologs.
Yue Wu, Ziqi Sun, Feiyan Qi, Mingbo Zhao, Wenzhao Dong, Bingyan Huang, Zheng Zheng, Xinyou Zhang   +7 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

The TaCLE24b peptide signaling cascade modulates lateral root development and drought tolerance in wheat

Nature Communications
Plant peptide hormones play an important role in regulating root development and stress responses. Here, we identify a root-derived CLAVATA3/Endosperm surrounding region-related (CLE) peptide TaCLE24b and its leucine-rich repeat receptor-like kinase ...
Wen Yang, Man Feng, Kuohai Yu, Jie Cao, Guangxian Cui, Yumei Zhang, Huiru Peng, Yingyin Yao, Zhaorong Hu, Zhongfu Ni, Feng Qin, Fuminori Takahashi, Qixin Sun, Mingming Xin   +13 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Molecular breeding

, 2017
Molecular Breeding is an international journal focused on applications of plant molecular biology: research most likely leading to practical applications with demonstrable benefits for farmers, the seed and processing industries, the environment and the ...
TUBEROSA, ROBERTO, SALVI, SILVIO, MACCAFERRI, MARCO   +2 more
core   +1 more source

Epistatic interaction has the reverse effects with its constitutive quantitative trait loci

Scientific Reports
Epistasis is one of important genetic components for a quantitative trait in plant. Eshed and Zamir found negative epistatic interactions of quantitative trait loci in Tomato first.
Yuanyuan Liu, Bihuang Zhu, Jichun Tang, Lilong Huang, Guodong Chen, Leyi Chen, Suhong Bu, Haitao Zhu, Zupei Liu, Zhan Li, Lijun Meng, Guifu Liu, Shaokui Wang   +12 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Multi-tissue analysis identifies mitochondrial genes in chicken aging-induced productivity decline

Journal of Animal Science and Biotechnology
Background Aging-related production decline is widely observed in poultry farming, making it challenging to prolong the laying cycle of hens. However, its genetic determinants remain unclear.
Mingyue Gao, Junnan Zhang, Boxuan Zhang, Xinwei Jiang, Bowen Niu, Conghao Zhong, Fangren Lan, Wenxin Zhang, Ning Yang, Congjiao Sun   +9 more
doaj   +1 more source