Results 41 to 50 of about 3,853,576 (297)

Identifying molecular pathways and candidate genes associated with knob traits by transcriptome analysis in the goose (Anser cygnoides)

Scientific Reports, 2021
Anser cygnoides has a spherical crest on the beak roof, which is described as knob. However, the mechanisms affecting knob morphology are unclear. Here, we investigated the phenotypic characteristics and molecular basis of knob-size differences in ...
Wangyang Ji, li E Hou, Xiaoya Yuan, Tiantian Gu, ZhuoYu Chen, Yu Zhang, Yang Zhang, Guohong Chen, Qi Xu, Wenming Zhao   +9 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

QTL epistasis plays a role of homeostasis on heading date in rice

Scientific Reports
If there was no gene interaction, the gene aggregation effect would increase infinitely with the increase of gene number. Epistasis avoids the endless accumulation of gene effects, playing a role of homeostasis.
Lilong Huang, Jichun Tang, Bihuang Zhu, Guodong Chen, Leyi Chen, Suhong Bu, Haitao Zhu, Zupei Liu, Zhan Li, Lijun Meng, Guifu Liu, Shaokui Wang   +11 more
doaj   +1 more source

ShORR-1, a Novel Tomato Gene, Confers Enhanced Host Resistance to Oidium neolycopersici

Frontiers in Plant Science, 2019
A previous complementary cDNA-amplified fragment length polymorphism (cDNA-AFLP) analysis examined responses to the powdery mildew pathogen Oidium neolycopersici (On) of the resistant cultivar Solanum habrochiates G1.1560, carrying the Ol-1 resistance ...
Yi Zhang, Yi Zhang, Kedong Xu, Kedong Xu, Dongli Pei, Deshui Yu, Deshui Yu, Ju Zhang, Ju Zhang, Xiaoli Li, Xiaoli Li, Guo Chen, Guo Chen, Hui Yang, Hui Yang, Wenjie Zhou, Wenjie Zhou, Chengwei Li   +17 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Genome-wide characterization of AhBAG genes in peanut reveals their role in bacterial wilt resistance and hormone response

BMC Plant Biology
Background The BAG gene family, encoding Bcl-2-associated anti-apoptotic proteins, plays pivotal roles in regulating plant growth, development, and stress responses.
Kai Zhao, Yanzhe Li, Jinzhi Wang, Yue Tu, Zenghui Cao, Xingli Ma, Fangping Gong, Zhongfeng Li, Lin Zhang, Ding Qiu, Xingguo Zhang, Rui Ren, Kunkun Zhao, Dongmei Yin   +13 more
doaj   +1 more source

Multiple responses contribute to the enhanced drought tolerance of the autotetraploid Ziziphus jujuba Mill. var. spinosa

Cell & Bioscience, 2021
Background Polyploid plants often exhibit enhanced stress tolerance. The underlying physiological and molecular bases of such mechanisms remain elusive.
Meng Li, Chenxing Zhang, Lu Hou, Weicong Yang, Songshan Liu, Xiaoming Pang, Yingyue Li   +6 more
doaj   +1 more source

Extraterritorial prospecting and territory defence in cooperatively breeding meerkats [PDF]

, 2012
In group living animals where natal dispersal is delayed, prospecting allows individuals to asses their future dispersal and breeding opportunities and, in males of some species, may minimize the costs of delaying dispersal by enabling extra-group ...

core   +2 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source