Results 51 to 60 of about 3,853,576 (297)

A transcriptomic map of ligand-receptor interactions within bovine antral follicles predicts intrafollicular factors for improving oocyte quality

Journal of Animal Science and Biotechnology
Background The ovarian follicle is an enclosed microenvironment that ensures oocyte growth and maturation, making it essential for female fertility. Normal folliculogenesis development and oocyte maturation strictly rely on orchestrated intercellular ...
Zhaochen Wang, Zhenni Zhang, Yawen Tang, Jian Cui, Meiqiang Chu, Jianhui Tian, Yinjuan Wang, Lei An   +7 more
doaj   +1 more source

Next-generation sequencing of amplicons is a rapid and reliable method for the detection of polymorphisms relevant for barley breeding

, 2022
Modern plant breeding is based on the detection of traits at the molecular level so that the selection process can be accelerated. Methods that allow the rapid and high-throughput analysis of such traits are therefore useful for plant breeders and ...
Fischer, R., Schröper, F., Fritsch, L., Hansen, C., Soeur, R., Schillberg, S.   +5 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

RPAD locus controls prostrate growth habit in Oryza nivara

The Plant Genome
The development of ideal plant architecture is crucial for optimizing grain yield in crop breeding. The transition from prostrate growth habit in wild rice to erect growth habit in cultivated rice is one of the important events during rice domestication.
Yuntao Liu, Fang Yao, Jun Zou, Daokuan Guo, Wanxia Jiang, Jinjian Fan, Ruichao Li, Zhenbin Yang, Yurong Ma, Haodong Deng, Jiayu Huang, Lubin Tan   +11 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Inferring multilayer interactome networks shaping phenotypic plasticity and evolution

Nature Communications, 2021
Genetic plasticity drives phenotypic differences. Here, the authors develop a framework to quantify the individual and combinatorial contributions of SNPs on a phenotype of interest and use it to identify SNP-SNP interactions associated with variations ...
Dengcheng Yang, Yi Jin, Xiaoqing He, Ang Dong, Jing Wang, Rongling Wu   +5 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

International Symposium on Evolutionary Breeding in Cereals [PDF]

, 2013
Evolutionary plant breeding has a long history, but has so far not become part of mainstream breeding research, nor has it been implemented in practice to any substantial degree.

core   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Decoding the gene regulatory network of endosperm differentiation in maize

Nature Communications
The persistent cereal endosperm constitutes the majority of the grain volume. Dissecting the gene regulatory network underlying cereal endosperm development will facilitate yield and quality improvement of cereal crops.
Yue Yuan, Qiang Huo, Ziru Zhang, Qun Wang, Juanxia Wang, Shuaikang Chang, Peng Cai, Karen M. Song, David W. Galbraith, Weixiao Zhang, Long Huang, Rentao Song, Zeyang Ma   +12 more
doaj   +1 more source