Results 71 to 80 of about 3,853,576 (297)

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Genome-wide identification and functional analysis of the SAMS gene family in peanut reveal the role of Ah6Q1KS5 in resistance to bacterial wilt

BMC Plant Biology
Background S-adenosyl-L-methionine synthetase (SAMS) catalyzes the synthesis of S-adenosylmethionine (SAM), a universal methyl donor, and regulate plant growth, development, and stress responses.
Yanzhe Li, Sasa Hu, Kai Zhao, Yue Tu, Lujie Gao, Zenghui Cao, Xingli Ma, Fangping Gong, Zhongfeng Li, Ding Qiu, Rui Ren, Kunkun Zhao, Dongmei Yin   +12 more
doaj   +1 more source

DNA barcode trnH-psbA is a promising candidate for efficient identification of forage legumes and grasses

BMC Research Notes, 2020
Objective Grasslands are widespread ecosystems that fulfil many functions. Plant species richness (PSR) is known to have beneficial effects on such functions and monitoring PSR is crucial for tracking the effects of land use and agricultural management ...
Miguel Loera-Sánchez, Bruno Studer, Roland Kölliker   +2 more
doaj   +1 more source

Rice molecular breeding laboratories in the genomics era: Current status and future considerations [PDF]

, 2008
Using DNA markers in plant breeding with marker-assisted selection (MAS) could greatly improve the precision and efficiency of selection, leading to the accelerated development of new crop varieties.
McNally, K.L., Virk, P.S., Vera Cruz, C.M., Mackill, D.J., Collard, B.C.Y.   +4 more
core   +2 more sources

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Genomic characterisation of the metal tolerance protein gene family and elucidation of functional role in heavy metal tolerance and accumulation in Coptis chinensis

Frontiers in Plant Science
Metal tolerance protein (MTP) family members, functioning as plant divalent cation transporters, play essential roles in maintaining heavy metal homeostasis and tolerance. This study presents a novel comprehensive genomic characterisation of the MTP gene
Yi Zhang, Yi Zhang, Lili Wang, Jinke Zhang, Chenxi Wang, Yue Fan, Haohao Cao, Huanyu Zhang, Yuchen Ma, Haoyu Wang, Jiaxin Kang, Yige Jiao, Xinxin Shangguan, Xiaoli Li, Kedong Xu, Kedong Xu   +15 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

CGIAR Excellence in Breeding Platform - Plan of Work and Budget 2020 [PDF]

, 2020
At the end of 2019, all CGIAR centers had submitted improvement plans based on an EiB template and in close collaboration with EiB staff while – in a parallel process with breeding programs, funders and private sector representatives – a vision for ...
CGIAR Excellence in Breeding Platform
core  

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source