Results 251 to 260 of about 4,011,919 (357)

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source

Molecular chaperones: Guardians of tumor suppressor stability and function. [PDF]

Oncotarget
Heritz JA, Backe SJ, Mollapour M.
europepmc   +1 more source

Molecular chaperones and their denaturing effect on client proteins. [PDF]

J Biomol NMR, 2021
Hiller S.
europepmc   +1 more source

DNAJC7, a Molecular Chaperone Protein that Modulates Protein Misfolding in Amyotrophic Lateral Sclerosis (ALS)

, 2020
Meaghan Kathleen Stoltz
openalex   +1 more source

Referee report. For: Molecular chaperones: guardians of the proteome in normal and disease states [version 1; referees: 2 approved]

, 2015
José M. Barral
openalex   +1 more source

Experimental Milestones in the Discovery of Molecular Chaperones as Polypeptide Unfolding Enzymes.

Annual Review of Biochemistry, 2016
Andrija Finka, Rayees U. H. Mattoo, P. Goloubinoff   +2 more
semanticscholar   +1 more source

Expression, Purification, and Microscopy‐Based Assays for Engineered Recombinant Tyrosinated, Detyrosinated, and Δ2 Human Tubulin

Cytoskeleton, EarlyView.
ABSTRACT Microtubules are noncovalent polymers assembled from α/β tubulin dimers. Their structure, dynamics and interaction with effectors are regulated through the expression of diverse tubulin isotypes and chemically diverse posttranslational modifications, also known as the “tubulin code.” Understanding the biophysical correlates between tubulin ...
Jiayi Chen, Agnieska Szyk, Antonina Roll‐Mecak   +2 more
wiley   +1 more source

Potential of molecular chaperones for treating Alzheimer's disease. [PDF]

Neural Regen Res
Chen G, Johansson J.
europepmc   +1 more source

Influence of the conserved disulphide bond, exposed to the putative binding pocket, on the structure and function of the immunoglobulin-like molecular chaperone Caf1M of Yersinia pestis [PDF]

, 1997
V.P. Zav′yalov, T.V. Chernovskaya, David A. Chapman, Andrey V. Karlyshev, Sheila MacIntyre, Anton V. Zavialov, Anatoly M. Vasiliev, Alexander I. Denesyuk, Galina A. Zav’yalova, I.V. Dudich, Timo Korpela, Vyacheslav M. Abramov   +11 more
openalex   +1 more source

Targeting Hsp90 with cemdomespib reduces seizure burden and alters disease course in preclinical epilepsy models

Epilepsia, EarlyView.
Abstract Objective Epilepsy is a chronic neurological disorder characterized by recurrent seizures and frequent cognitive and psychiatric comorbidities. Although current antiseizure medications provide symptomatic relief, they fail to prevent or modify epileptogenesis.
Yara Sheeni, Prince Kumar Singh, Sereen Sandouka, Taige Zhang, Alina Nemirovski, Aseel Saadi, Rhoda Olowe Taiwo, Matthew C. Walker, Tawfeeq Shekh‐Ahmad   +8 more
wiley   +1 more source