Results 1 to 10 of about 7,940,505 (313)

Prostate Cancer Radiogenomics—From Imaging to Molecular Characterization

International Journal of Molecular Sciences, 2021
Radiomics and genomics represent two of the most promising fields of cancer research, designed to improve the risk stratification and disease management of patients with prostate cancer (PCa).
Octavian Sabin Tataru, Giuseppe Lucarelli, Mihai Dorin Vartolomei   +2 more
exaly   +2 more sources

Methicillin-Resistant Staphylococcus aureus: Molecular Characterization, Evolution, and Epidemiology

Clinical Microbiology Reviews, 2018
Staphylococcus aureus, a major human pathogen, has a collection of virulence factors and the ability to acquire resistance to most antibiotics. This ability is further augmented by constant emergence of new clones, making S. aureus a “superbug.” Clinical
Kunyan Zhang
exaly   +2 more sources

Circulating tumor DNA sequencing provides comprehensive mutation profiling for pediatric central nervous system tumors

npj Precision Oncology, 2022
Molecular profiling of childhood CNS tumors is critical for diagnosis and clinical management, yet tissue access is restricted due to the sensitive tumor location.
Erin R. Bonner, Robin Harrington, Augustine Eze, Miriam Bornhorst, Cassie N. Kline, Heather Gordish-Dressman, Adam Dawood, Biswajit Das, Li Chen, Rini Pauly, P. Mickey Williams, Chris Karlovich, Amanda Peach, D’andra Howell, James Doroshow, Lindsay Kilburn, Roger J. Packer, Sabine Mueller, Javad Nazarian   +18 more
doaj   +1 more source

Comprehensive clinical and molecular characterization of claudin 18.2 expression in advanced gastric or gastroesophageal junction cancer

ESMO Open, 2023
Background We conducted comprehensive clinical and molecular characterization of claudin 18.2 expression (CLDN18.2) in advanced gastric or gastroesophageal junction cancer (GC/GEJC).
Y. Kubota, A. Kawazoe, S. Mishima, Y. Nakamura, D. Kotani, Y. Kuboki, H. Bando, T. Kojima, T. Doi, T. Yoshino, T. Kuwata, K. Shitara   +11 more
semanticscholar   +1 more source

A comparative analysis exposes an amplification delay distinctive to SARS-CoV-2 Omicron variants of clinical and public health relevance

Emerging Microbes and Infections, 2023
Mutations in the SARS-CoV-2 genome may negatively impact a diagnostic test, have no effect, or turn into an opportunity for rapid molecular screening of variants.
K.L. Brown, A. Ceci, C. Roby, R. Briggs, D. Ziolo, R. Korba, R. Mejia, S.T. Kelly, D. Toney, M.J. Friedlander, C.V. Finkielstein   +10 more
doaj   +1 more source

Development and performance evaluation of whole-genome sequencing with paired-end and mate-pair strategies in molecular characterization of GM crops: One GM rice 114-7-2 line as an example

Food Chemistry: Molecular Sciences, 2022
Basic data for the safety assessment of transgenic line involves the molecular characterization of the integration site of exogenous DNA, flanking sequences, copy number, and unintended plasmid backbone residues.
Hanwen Zhang, Yuchen Zhang, Wenting Xu, Rong Li, Dabing Zhang, Litao Yang   +5 more
doaj   +1 more source

Molecular characterization of colorectal cancer related peritoneal metastatic disease

Nature Communications, 2022
A significant proportion of colorectal cancer (CRC) patients develop peritoneal metastases (PM) in the course of their disease. PMs are associated with a poor quality of life, significant morbidity and dismal disease outcome.
K. Lenos, S. Bach, Leandro Ferreira Moreno, Sanne ten Hoorn, N. Sluiter, S. Bootsma, F. A. Vieira Braga, Lisanne E. Nijman, Tom van den Bosch, D. M. Miedema, E. van Dijk, B. Ylstra, R. Kulicke, Fred P. Davis, Nicolas Stransky, G. Smolen, R. R. J. Coebergh van den Braak, J. Ijzermans, J. Martens, S. Hallam, A. Beggs, G. Kops, N. Lansu, V. Bastiaenen, C. Klaver, Maria C. Lecca, Khalid El Makrini, C. Elbers, M. Dings, C. V. van Noesel, O. Kranenburg, J. Medema, J. Koster, L. Koens, C. Punt, P. Tanis, I. D. de Hingh, M. Bijlsma, J. Tuynman, L. Vermeulen   +39 more
semanticscholar   +1 more source

An update on the epidemiology, molecular characterization, diagnosis, and screening strategies for early-onset colorectal cancer

Gastroenterology, 2021
Rising trends in the incidence and mortality of early-onset CRC in those who are ages less than 50 years have been well-established. These trends have spurred intense investigation focused on elucidating the epidemiology and characteristics of early ...
A. Burnett-Hartman, Jeffrey-K Lee, J. Demb, Samir Gupta   +3 more
semanticscholar   +1 more source

PIMGAVir and Vir-MinION: Two Viral Metagenomic Pipelines for Complete Baseline Analysis of 2nd and 3rd Generation Data

Viruses, 2022
The taxonomic classification of viral sequences is frequently used for the rapid identification of pathogens, which is a key point for when a viral outbreak occurs.
Emilio Mastriani, Kathrina Mae Bienes, Gary Wong, Nicolas Berthet   +3 more
doaj   +1 more source

HPV-Negative Adenocarcinomas of the Uterine Cervix: From Molecular Characterization to Clinical Implications

International Journal of Molecular Sciences, 2022
Cervical cancer is the fourth most common cancer in women. It is the leading cause of female deaths in developing countries. Most of these cervical neoplasms are represented by squamous lesions.
Luca Giannella, J. Di Giuseppe, G. Delli Carpini, Camilla Grelloni, M. Fichera, Gianmarco Sartini, Serena Caimmi, Leonardo Natalini, A. Ciavattini   +8 more
semanticscholar   +1 more source