Results 1 to 10 of about 2,606,187 (305)

Circulating tumor DNA sequencing provides comprehensive mutation profiling for pediatric central nervous system tumors

npj Precision Oncology, 2022
Molecular profiling of childhood CNS tumors is critical for diagnosis and clinical management, yet tissue access is restricted due to the sensitive tumor location.
Erin R. Bonner, Robin Harrington, Augustine Eze, Miriam Bornhorst, Cassie N. Kline, Heather Gordish-Dressman, Adam Dawood, Biswajit Das, Li Chen, Rini Pauly, P. Mickey Williams, Chris Karlovich, Amanda Peach, D’andra Howell, James Doroshow, Lindsay Kilburn, Roger J. Packer, Sabine Mueller, Javad Nazarian   +18 more
doaj   +1 more source

A comparative analysis exposes an amplification delay distinctive to SARS-CoV-2 Omicron variants of clinical and public health relevance

Emerging Microbes and Infections, 2023
Mutations in the SARS-CoV-2 genome may negatively impact a diagnostic test, have no effect, or turn into an opportunity for rapid molecular screening of variants.
K.L. Brown, A. Ceci, C. Roby, R. Briggs, D. Ziolo, R. Korba, R. Mejia, S.T. Kelly, D. Toney, M.J. Friedlander, C.V. Finkielstein   +10 more
doaj   +1 more source

Development and performance evaluation of whole-genome sequencing with paired-end and mate-pair strategies in molecular characterization of GM crops: One GM rice 114-7-2 line as an example

Food Chemistry: Molecular Sciences, 2022
Basic data for the safety assessment of transgenic line involves the molecular characterization of the integration site of exogenous DNA, flanking sequences, copy number, and unintended plasmid backbone residues.
Hanwen Zhang, Yuchen Zhang, Wenting Xu, Rong Li, Dabing Zhang, Litao Yang   +5 more
doaj   +1 more source

PIMGAVir and Vir-MinION: Two Viral Metagenomic Pipelines for Complete Baseline Analysis of 2nd and 3rd Generation Data

Viruses, 2022
The taxonomic classification of viral sequences is frequently used for the rapid identification of pathogens, which is a key point for when a viral outbreak occurs.
Emilio Mastriani, Kathrina Mae Bienes, Gary Wong, Nicolas Berthet   +3 more
doaj   +1 more source

Channel characterization for 1D molecular communication with two absorbing receivers [PDF]

, 2020
This letter develops a one-dimensional (1D) diffusion-based molecular communication system to analyze channel responses between a single transmitter (TX) and two fully-absorbing receivers (RXs).
Fang, Yuting, Huang, Xinyu, Noel, Adam, Yang, Nan   +3 more
core   +2 more sources

Thermal ablation in pancreatic cancer: A scoping review of clinical studies

Frontiers in Oncology, 2022
BackgroundPancreatic cancer is a deadly cancer with a 5-year survival rate less than 10%. Only 20% of patients are eligible to receive surgery at diagnosis. Hence, new therapies are needed to improve outcomes for non-surgical candidates. Thermal ablation
William Farmer, William Farmer, Gary Hannon, Gary Hannon, Shubhrima Ghosh, Shubhrima Ghosh, Adriele Prina-Mello, Adriele Prina-Mello, Adriele Prina-Mello   +8 more
doaj   +1 more source

Comparative Methylome Analysis of Campylobacter jejuni Strain YH002 Reveals a Putative Novel Motif and Diverse Epigenetic Regulations of Virulence Genes

Frontiers in Microbiology, 2020
Campylobacter jejuni is a major cause of foodborne gastroenteritis worldwide inflicting palpable socioeconomic costs. The ability of this pathogen to successfully infect its hosts is determined not only by the presence of specific virulence genes but ...
Sandeep Ghatak, Cheryl M. Armstrong, Sue Reed, Yiping He   +3 more
doaj   +1 more source

Intra-Host Diversity of SARS-Cov-2 Should Not Be Neglected: Case of the State of Victoria, Australia

Viruses, 2021
Since the identification of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as the etiological agent of the current COVID-19 pandemic, a rapid and massive effort has been made to obtain the genomic sequences of this virus to monitor (in near
Alix Armero, Nicolas Berthet, Jean-Christophe Avarre   +2 more
doaj   +1 more source

A paired-end whole-genome sequencing approach enables comprehensive characterization of transgene integration in rice

Communications Biology, 2022
Coupling paired-end whole-genome sequencing with droplet digital PCR enabled precise identification of a transgene insertion in the genetically modified rice event G281 on chromosome 3 and the potential for exploring the native gene integration.
Wenting Xu, Hanwen Zhang, Yuchen Zhang, Ping Shen, Xiang Li, Rong Li, Litao Yang   +6 more
doaj   +1 more source

Detection of Shiga Toxin 2 Produced by Escherichia coli in Foods Using a Novel AlphaLISA

Toxins, 2018
Amplified luminescent proximity homogenous assay-linked immunosorbent assay (AlphaLISA) is comprised of a bead-based immunoassay that is used for small molecule detection.
Cheryl M. Armstrong, Leah E. Ruth, Joseph A. Capobianco, Terence P. Strobaugh, Fernando M. Rubio, Andrew G. Gehring   +5 more
doaj   +1 more source