Results 21 to 30 of about 7,940,505 (313)

Molecular characterization of phagosomes.

Journal of Biological Chemistry, 1994
The transformation of newly formed phagosomes into mature phagolysosomes is a process that involves a complex series of interactions between phagosomes and other vacuolar organelles. The machinery required by phagosomes to mediate these interactions is poorly understood.
Desjardins, M., Celis, J.E., van Meer, G., Dieplinger, H., Jahraus, A., Griffiths, G., Huber, L.A.   +6 more
openaire   +4 more sources

Molecular Characterization of the PmrA Regulon [PDF]

Journal of Biological Chemistry, 1999
The two-component system PmrA/PmrB of Salmonella enterica controls expression of several loci including those mediating modifications in the lipopolysaccharide that result in polymyxin resistance. To gain insight in the regulation of polymyxin resistance, we mapped the transcription start sites of the PmrA-regulated genes pmrC, pmrG, pbgPE, and ugd and
M M, Wösten, E A, Groisman
openaire   +2 more sources

Integrated genomic and molecular characterization of cervical cancer

Nature, 2017
Cervical cancer remains one of the leading causes of cancer-related deaths worldwide. Here we report the extensive molecular characterization of 228 primary cervical cancers, one of the largest comprehensive genomic studies of cervical cancer to date. We
R. Burk, Zigui Chen, Charles Saller, Katherine Tarvin, A. Carvalho, C. Scapulatempo-Neto, H. C. Silveira, J. Fregnani, C. Creighton, Matthew L. Anderson, Patricia D. Castro, Sophia S. Wang, C. Yau, C. Benz, Gordon Robertson, K. Mungall, Lynette Lim, R. Bowlby, S. Sadeghi, Denise Brooks, Payal Sipahimalani, Richard Mar, Adrian Ally, A. Clarke, A. Mungall, Angela Tam, Darlene Lee, E. Chuah, J. Schein, Kane Tse, K. Kasaian, Yussanne Ma, M. Marra, Michael Mayo, M. Balasundaram, N. Thiessen, Noreen Dhalla, R. Carlsen, Richard A. Moore, R. Holt, Steven J. M. Jones, Tina Wong, A. Pantazi, Michael G Parfenov, R. Kucherlapati, Angela Hadjipanayis, J. Seidman, M. Kucherlapati, X. Ren, A. W. Xu, Lixing Yang, P. Park, Semin Lee, B. Rabeno, L. Huelsenbeck-Dill, M. Borowsky, M. Cadungog, M. Iacocca, N. Petrelli, P. Swanson, A. Ojesina, X. Le, G. Sandusky, S. Adebamowo, Teniola Akeredolu, C. Adebamowo, Sheila M. Reynolds, I. Shmulevich, C. Shelton, D. Crain, D. Mallery, Erin E. Curley, J. Gardner, R. Penny, S. Morris, T. Shelton, Jia Liu, Laxmi Lolla, Sudha Chudamani, Ye Wu, M. Birrer, M. McLellan, Matthew H. Bailey, Christopher A. Miller, Matthew A. Wyczalkowski, R. Fulton, Catrina C. Fronick, Charles Lu, E. Mardis, Elizabeth L. Appelbaum, Heather K. Schmidt, L. Fulton, M. Cordes, Tiandao Li, L. Ding, R. Wilson, J. Rader, B. Behmaram, D. Uyar, W. Bradley, J. Wrangle, A. Pastore, D. Levine, F. Dao, Jianjiong Gao, N. Schultz, C. Sander, M. Ladanyi, M. Einstein, R. Teeter, S. Benz, N. Wentzensen, Ina Felau, J. Zenklusen, C. Bodelon, J. Demchok, Liming Yang, Margi Sheth, M. Ferguson, R. Tarnuzzer, Hannah P. Yang, M. Schiffman, Jiashan Zhang, Zhining Wang, Tanja Davidsen, O. Olaniyan, C. Hutter, H. Sofia, D. Gordenin, Kin Chan, S. Roberts, L. Klimczak, C. Van Waes, Zhong Chen, Anthony D Saleh, Hui Cheng, J. Parfitt, J. Bartlett, Monique Albert, A. Arnaout, H. Sekhon, S. Gilbert, Myron Peto, J. Myers, Jodi Harr, J. Eckman, Julie Bergsten, Kelinda Tucker, L. A. Zach, B. Karlan, J. Lester, S. Orsulic, Qiang Sun, R. Naresh, T. Pihl, Yunhu Wan, H. Zaren, J. Sapp, Judy Miller, Paul Drwiega, Bradley A. Murray, Hailei Zhang, A. Cherniack, C. Sougnez, C. Pedamallu, Lee T. Lichtenstein, M. Meyerson, M. Noble, David I Heiman, D. Voet, G. Getz, G. Saksena, Jaegil Kim, J. Shih, Juok Cho, M. Lawrence, Nils Gehlenborg, Pei Lin, R. Beroukhim, S. Frazer, S. Gabriel, S. Schumacher, K. Leraas, T. Lichtenberg, E. Zmuda, Jay Bowen, Jessica Frick, J. Gastier-Foster, L. Wise, M. Gerken, N. Ramirez, Ludmila V. Danilova, Leslie M. Cope, S. Baylin, H. Salvesen, C. Vellano, Z. Ju, L. Diao, Hao Zhao, Zechen Chong, Michael C. Ryan, Emmanuel Martínez-Ledesma, R. Verhaak, L. Byers, Yuan Yuan, Ken Chen, Shiyun Ling, G. Mills, Yiling Lu, Rehan Akbani, S. Seth, Han Liang, Jing Wang, Leng Han, J. Weinstein, C. Bristow, Wei Zhang, Harshad S. Mahadeshwar, Huandong Sun, Jiabin Tang, Jianhua Zhang, Xingzhi Song, A. Protopopov, K. Shaw, L. Chin, Oluwole Olabode, P. Disaia, Amie Radenbaugh, D. Haussler, Jingchun Zhu, J. Stuart, P. Chalise, D. Koestler, B. Fridley, A. Godwin, R. Madan, G. Ciriello, C. Martinez, Kelly J. Higgins, T. Bocklage, T. Auman, C. Perou, Donghui Tan, J. Parker, K. Hoadley, M. Wilkerson, P. Mieczkowski, Tara J. Skelly, Umadevi Veluvolu, N. Hayes, K. Rathmell, A. Hoyle, J. Simons, Junyuan Wu, Lisle E. Mose, Matthew G. Soloway, S. Balu, S. Meng, S. Jefferys, T. Bodenheimer, Yan Shi, J. Roach, L. Thorne, L. Boice, Meijuan Huang, Corbin D. Jones, R. Zuna, Joan L. Walker, C. Gunderson, Carie Snowbarger, David Brown, K. Moxley, K. Moore, Kelsi Andrade, L. Landrum, R. Mannel, S. McMeekin, S. Johnson, T. Nelson, E. Elishaev, R. Dhir, Robert A. Edwards, R. Bhargava, D. Tiezzi, J. M. Andrade, H. Noushmehr, C. Carlotti, D. Tirapelli, D. Weisenberger, D. J. Van Den Berg, D. Maglinte, M. Bootwalla, Phillip H. Lai, T. Triche, E. Swisher, K. Agnew, C. Shelley, P. Laird, J. Schwarz, P. Grigsby, D. Mutch   +300 more
semanticscholar   +2 more sources

Detection of Shiga Toxin 2 Produced by Escherichia coli in Foods Using a Novel AlphaLISA

Toxins, 2018
Amplified luminescent proximity homogenous assay-linked immunosorbent assay (AlphaLISA) is comprised of a bead-based immunoassay that is used for small molecule detection.
Cheryl M. Armstrong, Leah E. Ruth, Joseph A. Capobianco, Terence P. Strobaugh, Fernando M. Rubio, Andrew G. Gehring   +5 more
doaj   +1 more source

A paired-end whole-genome sequencing approach enables comprehensive characterization of transgene integration in rice

Communications Biology, 2022
Coupling paired-end whole-genome sequencing with droplet digital PCR enabled precise identification of a transgene insertion in the genetically modified rice event G281 on chromosome 3 and the potential for exploring the native gene integration.
Wenting Xu, Hanwen Zhang, Yuchen Zhang, Ping Shen, Xiang Li, Rong Li, Litao Yang   +6 more
doaj   +1 more source

Comprehensive Molecular Characterization of Human Colon and Rectal Cancer

Nature, 2012
To characterize somatic alterations in colorectal carcinoma, we conducted a genome-scale analysis of 276 samples, analysing exome sequence, DNA copy number, promoter methylation and messenger RNA and microRNA expression.
D. Muzny, M. Bainbridge, Kyle Chang, H. Dinh, J. Drummond, G. Fowler, C. Kovar, L. Lewis, M. Morgan, I. Newsham, J. Reid, J. Santibanez, E. Shinbrot, L. Treviño, Yuan-qing Wu, Min Wang, P. Gunaratne, L. Donehower, C. Creighton, D. Wheeler, R. Gibbs, M. Lawrence, D. Voet, R. Jing, K. Cibulskis, A. Sivachenko, P. Stojanov, A. McKenna, E. Lander, S. Gabriel, L. Ding, R. Fulton, D. Koboldt, T. Wylie, Jason R. Walker, D. Dooling, L. Fulton, K. D. Delehaunty, Catrina C. Fronick, Ryan T. Demeter, E. Mardis, R. Wilson, Andy Chu, Hye-Jung E. Chun, A. Mungall, E. Pleasance, A. G. Robertson, D. Stoll, M. Balasundaram, I. Birol, Y. Butterfield, E. Chuah, R. Coope, Noreen Dhalla, R. Guin, Carrie Hirst, M. Hirst, R. Holt, Darlene Lee, H. Li, Michael Mayo, Richard A. Moore, J. Schein, Jared R. Slobodan, Angela Tam, N. Thiessen, R. Varhol, Thomas Zeng, Yongjun Zhao, Steven J. M. Jones, M. Marra, A. Bass, A. Ramos, G. Saksena, A. Cherniack, S. Schumacher, B. Tabak, S. Carter, Nam Pho, Huy L. Nguyen, R. Onofrio, A. Crenshaw, K. Ardlie, R. Beroukhim, W. Winckler, M. Meyerson, A. Protopopov, Angela Hadjipanayis, E. Lee, Ruibin Xi, Lixing Yang, X. Ren, N. Sathiamoorthy, Peng-Chieh Chen, Psalm S. Haseley, Yonghong Xiao, Semin Lee, J. Seidman, L. Chin, P. Park, R. Kucherlapati, J. Auman, K. Hoadley, Ying Du, M. Wilkerson, Yan Shi, C. Liquori, S. Meng, Ling Li, Yidi J. Turman, M. D. Topal, Donghui Tan, S. Waring, Elizabeth Buda, Jesse L. Walsh, Corbin D. Jones, P. Mieczkowski, Darshan Singh, Junyuan Wu, Anisha Gulabani, Peter Dolina, T. Bodenheimer, A. Hoyle, J. Simons, Matthew G. Soloway, Lisle E. Mose, S. Jefferys, S. Balu, Brian O’Connor, J. Prins, Derek Y. Chiang, D. Hayes, C. Perou, T. Hinoue, D. Weisenberger, D. Maglinte, F. Pan, B. Berman, D. V. Berg, Hui Shen, T. Triche, S. Baylin, P. Laird, G. Getz, M. Noble, Doug Voat, Nils Gehlenborg, D. Dicara, Juinhua Zhang, Hailei Zhang, Chang-Jiun Wu, S. Y. Liu, S. Shukla, Lihua Zhou, Pei Lin, R. Park, Marc-Danie Nazaire, James Robinson, H. Thorvaldsdóttir, J. Mesirov, V. Thorsson, Sheila M. Reynolds, Brady Bernard, R. Kreisberg, Jake Lin, L. Iype, Ryan Bressler, Timo Erkkilä, M. Gundapuneni, Yuexin Liu, Adam Norberg, Thomas Robinson, Da Yang, Wei Zhang, I. Shmulevich, J. J. Ronde, N. Schultz, E. Cerami, G. Ciriello, A. Goldberg, Benjamin E. Gross, A. Jacobsen, Jianjiong Gao, B. Kaczkowski, Rileen Sinha, B. A. Aksoy, Y. Antipin, B. Reva, R. Shen, B. Taylor, M. Ladanyi, C. Sander, Rehan Akbani, Nianxiang Zhang, B. Broom, Tod D. Casasent, A. Unruh, Chris Wakefield, S. Hamilton, R. Cason, K. Baggerly, J. Weinstein, D. Haussler, C. Benz, Joshua M. Stuart, S. Benz, J. Z. Sanborn, Charles J. Vaske, Jingchun Zhu, C. Szeto, G. Scott, C. Yau, S. Ng, Theodore Goldstein, K. Ellrott, E. Collisson, A. E. Cozen, D. Zerbino, C. Wilks, B. Craft, P. Spellman, R. Penny, T. Shelton, M. Hatfield, S. Morris, P. Yena, C. Shelton, M. Sherman, J. Paulauskis, J. Gastier-Foster, Jay Bowen, N. Ramirez, Aaron D. Black, R. Pyatt, L. Wise, P. White, M. Bertagnolli, Jennifer Brown, T. Chan, Gerald C. Chu, Christine Czerwinski, F. Denstman, R. Dhir, A. Dörner, C. Fuchs, J. Guillem, M. Iacocca, H. Juhl, Andrew Kaufman, B. Kohl, X. Le, M. Mariano, Elizabeth N. Medina, M. Meyers, G. Nash, P. Paty, N. Petrelli, B. Rabeno, W. Richards, D. Solit, P. Swanson, L. Temple, J. Tepper, Richard A. Thorp, E. Vakiani, M. Weiser, J. Willis, G. Witkin, Z. Zeng, M. Zinner, C. Zornig, M. Jensen, R. Sfeir, A. Kahn, A. Chu, Prachi Kothiyal, Zhining Wang, E. Snyder, J. Pontius, T. Pihl, Brenda Ayala, M. Backus, Jessica L Walton, J. Whitmore, J. Baboud, D. Berton, M. Nicholls, D. Srinivasan, R. Raman, Stanley Girshik, Peter A. Kigonya, S. Alonso, Rashmi N. Sanbhadti, S. Barletta, J. Greene, D. Pot, K. Shaw, Laura A. L. Dillon, K. Buetow, Tanja Davidsen, J. Demchok, G. Eley, M. Ferguson, P. Fielding, C. Schaefer, Margi Sheth, Liming Yang, M. Guyer, B. Ozenberger, Jacqueline D. Palchik, Jane L. Peterson, H. Sofia, E. Thomson   +312 more
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Antibody Microarray for E. coli O157:H7 and Shiga Toxin in Microtiter Plates

Sensors, 2015
Antibody microarray is a powerful analytical technique because of its inherent ability to simultaneously discriminate and measure numerous analytes, therefore making the technique conducive to both the multiplexed detection and identification of ...
Andrew G. Gehring, Jeffrey D. Brewster, Yiping He, Peter L. Irwin, George C. Paoli, Tawana Simons, Shu-I Tu, Joseph Uknalis   +7 more
doaj   +1 more source

Transcriptomics of Listeria monocytogenes Treated With Olive Leaf Extract

Frontiers in Microbiology, 2021
Listeria monocytogenes is a regulated foodborne pathogen that is known to cause listeriosis, a disease associated with high mortality rates in humans.
Yanhong Liu, Ting Fang, Yujuan Suo, Shigang Gao, Gian Marco Baranzoni, Cheryl M. Armstrong   +5 more
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Comprehensive molecular characterization of muscle invasive bladder cancer

Cell, 2017
Summary We report a comprehensive analysis of 412 muscle-invasive bladder cancers characterized by multiple TCGA analytical platforms. Fifty-eight genes were significantly mutated, and the overall mutational load was associated with APOBEC-signature ...
A. G. Robertson, Jaegil Kim, H. Al-Ahmadie, J. Bellmunt, Guangwu Guo, A. Cherniack, T. Hinoue, P. Laird, K. Hoadley, Rehan Akbani, Mauro A. A. Castro, E. Gibb, R. Kanchi, D. Gordenin, S. Shukla, F. Sánchez-Vega, D. Hansel, B. Czerniak, V. Reuter, X. Su, B. Carvalho, Vinicius S. Chagas, K. Mungall, S. Sadeghi, C. Pedamallu, Yiling Lu, L. Klimczak, Jiexin Zhang, Caleb Choo, A. Ojesina, S. Bullman, K. Leraas, T. Lichtenberg, Catherine J. Wu, N. Schultz, G. Getz, M. Meyerson, G. Mills, D. McConkey, J. Weinstein, D. Kwiatkowski, S. Lerner, Monique Albert, I. Alexopoulou, Adrian Ally, T. Antic, M. Aron, M. Balasundaram, J. Bartlett, S. Baylin, Allison Beaver, I. Birol, L. Boice, M. Bootwalla, Jay Bowen, R. Bowlby, Denise Brooks, B. Broom, W. Bshara, E. Burks, F. Cárcano, R. Carlsen, B. Carvalho, A. Carvalho, E. Castle, Patrick Castro, J. Catto, D. Chesla, E. Chuah, Sudha Chudamani, V. Cortessis, S. Cottingham, D. Crain, Erin E. Curley, S. Daneshmand, J. Demchok, Noreen Dhalla, H. Djaladat, J. Eckman, Sophie C. Egea, J. Engel, Ina Felau, M. Ferguson, J. Gardner, J. Gastier-Foster, M. Gerken, C. Gomez-Fernandez, Jodi Harr, A. Hartmann, Lynn M. Herbert, T. Ho, R. Holt, C. Hutter, Steven J. M. Jones, M. Jordá, R. Kahnoski, K. Kasaian, Phillip H. Lai, B. Lane, Jia Liu, Laxmi Lolla, Y. Lotan, Fabiano R Lucchesi, Yussanne Ma, R. Machado, D. Maglinte, D. Mallery, M. Marra, S. Martin, Michael Mayo, A. Meraney, A. Moinzadeh, Richard A. Moore, Edna M. Mora Pinero, S. Morris, C. Morrison, A. Mungall, J. Myers, R. Naresh, P. O’Donnell, D. Parekh, J. Parfitt, J. Paulauskis, R. Penny, T. Pihl, S. Porten, Mario E. Quintero-Aguiló, N. Ramirez, W. Rathmell, K. Rieger-Christ, Charles Saller, A. Salner, G. Sandusky, C. Scapulatempo-Neto, J. Schein, A. Schuckman, N. Schultz, C. Shelton, T. Shelton, J. Simko, Parminder Singh, Payal Sipahimalani, N. Smith, H. Sofia, A. Sorcini, M. Stanton, G. Steinberg, R. Stoehr, T. Sullivan, Qiang Sun, Angela Tam, R. Tarnuzzer, Katherine Tarvin, H. Taubert, N. Thiessen, L. Thorne, Kane Tse, Kelinda Tucker, D. V. Berg, K. V. Kessel, S. Wach, Yunhu Wan, Zhining Wang, D. Weisenberger, L. Wise, Tina Wong, Ye Wu, Liming Yang, L. A. Zach, J. Zenklusen, Jiashan Zhang, E. Zmuda, E. Zwarthoff   +172 more
semanticscholar   +1 more source

Collaborative Ring Trial of the Applicability of a Reference Plasmid DNA Calibrant in the Quantitative Analysis of GM Maize Event MON810

Foods, 2022
Certified reference materials (CRMs) is one of the critical requirements in a quantitative analytical method, such as in the quantification of genetically modified (GM) contents in food/feed products.
Yanan Meng, Shu Wang, Jinchao Guo, Litao Yang   +3 more
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