Results 151 to 160 of about 137,804 (303)

The Molecular Clouds of M31

open access: yesThe Astrophysical Journal
Deep interferometric observations of CO and dust continuum emission are obtained with the Submillimeter Array at 230 GHz to investigate the physical nature of the giant molecular cloud (GMC) population in the Andromeda galaxy (M31).
Charles J. Lada   +3 more
doaj   +1 more source

Context‐Dependent Role of GDF15: GDF15+ Tumor‐Associated Macrophages Suppress OSCC Progression by Enhancing Phagocytosis

open access: yesAdvanced Science, EarlyView.
This study identifies GDF15+ TAMs as a cell subset mediating tumor regression after immunotherapy. Macrophage‐intrinsic GDF15 enhances phagocytosis and antigen cross‐presentation to CD8+ T cells through the NF‐κB signaling pathway, thereby inhibiting tumor progression.
Xinyu Zhou   +9 more
wiley   +1 more source

Oxygen fractionation in dense molecular clouds. [PDF]

open access: yesMon Not R Astron Soc, 2019
Loison JC   +15 more
europepmc   +1 more source

Myeloid‐Derived Grancalcin Promotes Periodontal Inflammation and Pathological Bone Remodeling in Periodontitis

open access: yesAdvanced Science, EarlyView.
Grancalcin (GCA), a myeloid‐derived protein, is enriched in gingival tissues of periodontitis patients and mouse models. Through interactions with CD44 and activation of MYH9, GCA promotes NF‐κB signaling and exacerbates periodontal inflammation and bone loss.
Min Zhou   +6 more
wiley   +1 more source

3D CMZ. III. Constraining the 3D Structure of the Central Molecular Zone via Molecular Line Emission and Absorption

open access: yesThe Astrophysical Journal
The Milky Way’s Central Molecular Zone (CMZ) is the largest concentration of dense molecular gas in the Galaxy, the structure of which is shaped by the complex interplay between Galactic-scale dynamics and extreme physical conditions.
Daniel L. Walker   +17 more
doaj   +1 more source

Molecular Clouds

open access: yesThe Astrophysical Journal, 1974
Peter Goldreich, John Kwan
openaire   +1 more source

SMAD4 Palmitoylation Drives a Metabolic‐Transcriptional Circuit to Promote Tumorigenesis and Confers Radiosensitivity in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang   +16 more
wiley   +1 more source

Mapping the Dense Molecular Gas toward 13 Supernova Remnants

open access: yesThe Astrophysical Journal
Supernova remnants (SNRs) can exert strong influence on molecular clouds (MCs) through interaction by shock wave and cosmic rays. In this paper, we present our mapping observation of HCO ^+ and $\mathrm{HCN}$ 1–0 lines toward 13 SNRs interacting with MCs,
Tian-Yu Tu, Yang Chen, Qian-Cheng Liu
doaj   +1 more source

A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity

open access: yesAdvanced Science, EarlyView.
This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu   +16 more
wiley   +1 more source

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