Results 91 to 100 of about 3,781,135 (297)

18 YEARS OF CONFORMATION RADIOTHERAPY AT NAGOYA UNIVERSITY HOSPITAL [PDF]

, 1996
1996-03-29Conformation radiotherapy is one of the best techniques for minimizing the radiation dose absorbed by the surrounding normal tissue while delivering a high dose to a cancerous target area.
KODAIRA, TSUYOSHI, OBATA, YASUNORI, ITO, YOSHlYUKI, KOBAYASHI, HIDETOSHI, YAMADA, TETSUYA, HORIKAWA, YOSHIMI, ISHIGAKI, TAKEO, MURAO, TAKAYUKI   +7 more
core   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Crystal structure of 6-hydroxy-5-(2-methoxyphenoxy)-2,2′-bipyrimidin-4(3H)-one

Acta Crystallographica Section E: Crystallographic Communications, 2016
In the title compound, C15H12N4O4, the dihedral angle between the heterocyclic rings is 12.60 (8)°, and that between the benzene ring and the adjacent heterocyclic ring is 85.14 (6)°.
Belakavadi K. Sagar, Hemmige S. Yathirajan, Jerry P. Jasinski, Christopher Glidewell   +3 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Conformation-dependent changes in DAT diffusion dynamics.

, 2019
Conformation-dependent changes in DAT diffusion dynamics.
Oleg Kovtun (1618660), Riley S. Ferguson (7907645), Sandra J. Rosenthal (1310463), Ian D. Tomlinson (1618675)   +3 more
core   +1 more source

Bifunctional organocatalysts for the asymmetric synthesis of axially chiral benzamides

Beilstein Journal of Organic Chemistry, 2017
Bifunctional organocatalysts bearing amino and urea functional groups in a chiral molecular skeleton were applied to the enantioselective synthesis of axially chiral benzamides via aromatic electrophilic bromination.
Ryota Miyaji, Yuuki Wada, Akira Matsumoto, Keisuke Asano, Seijiro Matsubara   +4 more
doaj   +1 more source

Cholic Acid-Conjugated Methylcellulose-Polyethylenimine Nano-Aggregates for Drug Delivery Systems

Nanomaterials, 2019
Cholic acid-conjugated methylcellulose-polyethylenimines (MCPEI-CAs) were synthesized and characterized for drug delivery systems. Their synthesis was confirmed by 1H NMR and FT-IR analysis.
Taewan Kim, Jaehong Park, Tae-il Kim
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Conformation of Circular DNA in Two Dimensions [PDF]

The conformation of circular DNA molecules of various lengths adsorbed in a 2D conformation on a mica surface is studied. The results confirm the conjecture that the critical exponent ν is topologically invariant and equal to the self-avoiding walk value
Witz, Guillaume, Adamcik, Jozef, Dietler, Giovanni, Rechendorff, Kristian   +3 more
core   +1 more source

Molecular epidemiology of cystic echinococcosis [PDF]

, 2003
Echinococcus granulosus exhibits substantial genetic diversity that has important implications for the design and development of vaccines, diagnostic reagents and drugs effective against this parasite.
McManus, D.P., Thompson, R.C.A., D. P. McMANUS, R. C. A. THOMPSON, McManus, D. P., Thompson, R. C. A.   +5 more
core   +1 more source