Results 171 to 180 of about 496,088 (311)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Solvent Environment Influences Molecular Conformation and Electron Transport in Peptides. [PDF]

J Phys Chem Lett
Samajdar R, Nadeem H, Moghe N, Shukla D, Schroeder CM.   +4 more
europepmc   +1 more source

The molecular conformation of silk fibroin regulates osteogenic cell behavior by modulating the stability of the adsorbed protein-material interface. [PDF]

Bone Res, 2021
Long Y, Cheng X, Jansen JA, Leeuwenburgh SGC, Mao J, Yang F, Chen L.   +6 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Molecular conformation engineering in central 8π-electron system toward unique aggregation-induced ultra-narrowband emission with a FWHM of 13 nm. [PDF]

Light Sci Appl
Liu L, Zhang H, Xiao C, Ma B, Li B, He X, Xiao G, Zou B, Tang B, Zhang H, Lam JWY, Tang BZ, Wang Z.   +12 more
europepmc   +1 more source

Reversible mechanical control of molecular conformation. [PDF]

Commun Chem, 2020
Bissette AJ.
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Monitoring the Molecular Conformation of Individual Amphotericin B Molecules in an Aggregated State by Raman Optical Activity. [PDF]

Anal Chem
Pajor K, Zając G, Fusè M, Mach-Liszka M, Arczewska M, Gagoś M, Onaka Y, Fujisawa T, Unno M, Baranska M, Machalska E.   +10 more
europepmc   +1 more source

Exploring the Molecular Conformation Space by Soft Molecule-Surface Collision. [PDF]

J Am Chem Soc, 2020
Anggara K, Zhu Y, Delbianco M, Rauschenbach S, Abb S, Seeberger PH, Kern K.   +6 more
europepmc   +1 more source

Conformation and molecular organization of humic acids in aqueous solutions

, 2012
This diploma thesis deals with the conformation and molecular organization of humic acids in aqueous solutions. Humic substances have heterogeneous and polydisperse nature, therefore their secondary chemical structure has not yet been defined properly ...
Věžníková, Kateřina
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