Results 191 to 200 of about 3,978,643 (305)

Insight into the stabilization mechanism of rice protein amyloid fibrils modification on soy protein isolate gels: Gel properties, microstructure, and molecular conformation. [PDF]

Food Chem X
Ma J, Wang L, Pan D, Wang K, Huo J, Ma X, Lu B, Yu X, Xiao Z.   +8 more
europepmc   +1 more source

Structural characterisation of molecular conformation and the incorporation of adatoms in an on-surface Ullmann-type reaction. [PDF]

Commun Chem, 2020
Judd CJ, Junqueira FLQ, Haddow SL, Champness NR, Duncan DA, Jones RG, Saywell A.   +6 more
europepmc   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

COSMIC: Molecular Conformation Space Modeling in Internal Coordinates with an Adversarial Framework. [PDF]

J Chem Inf Model
Kuznetsov M, Ryabov F, Schutski R, Shayakhmetov R, Lin YC, Aliper A, Polykovskiy D.   +6 more
europepmc   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Octaethyl vs Tetrabenzo Functionalized Ru Porphyrins on Ag(111): Molecular Conformation, Self-Assembly and Electronic Structure. [PDF]

J Phys Chem C Nanomater Interfaces
Meier D, Knecht P, Vezzoni Vicente P, Eratam F, Xu H, Lee TL, Generalov A, Riss A, Yang B, Allegretti F, Feulner P, Reichert J, Barth JV, Seitsonen AP, Duncan DA, Papageorgiou AC.   +15 more
europepmc   +1 more source

Altering the inhibitory kinetics and molecular conformation of maltase by Tangzhiqing (TZQ), a natural α-glucosidase inhibitor. [PDF]

BMC Complement Med Ther, 2020
Li Y, Zhang X, Wang R, Han L, Huang W, Shi H, Wang B, Li Z, Zou S.   +8 more
europepmc   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Gram matrix: an efficient representation of molecular conformation and learning objective for molecular pretraining. [PDF]

Brief Bioinform
Xiang W, Zhong F, Ni L, Zheng M, Li X, Shi Q, Wang D.   +6 more
europepmc   +1 more source