Results 251 to 260 of about 29,798,559 (305)

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Comparison of prognostication by IPSS-M, IPSS-R and AIPSS-MDS in the context of limited availability of molecular data in daily clinical practice. [PDF]

open access: yesAnn Hematol
Schulz F   +20 more
europepmc   +1 more source

Parallel molecular data storage by printing epigenetic bits on DNA. [PDF]

open access: yesNature
Zhang C   +9 more
europepmc   +1 more source

Hereditary diffuse gastric cancer spectrum associated with germline <i>CTNNA1</i> loss of function revealed by clinical and molecular data from 351 carrier families and over 37 000 non-carrier controls. [PDF]

open access: yesGut
Lobo S   +55 more
europepmc   +1 more source

Analysis of Spatial Molecular Data

2023
Digital analysis of pathology whole-slide images has been recently gaining interest in the context of cancer diagnosis and treatment. In particular, deep learning methods have demonstrated significant potential in supporting pathology analysis, recently detecting molecular traits never before recognized in pathology H&E whole-slide images (WSIs ...
Alona, Levy-Jurgenson   +3 more
openaire   +2 more sources

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