Results 151 to 160 of about 34,759 (340)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

A single molecular descriptor to predict solution behavior of therapeutic antibodies. [PDF]

open access: yesSci Adv, 2020
Kingsbury JS   +10 more
europepmc   +1 more source

Indices analysis of hexa organic molecular structures together with fundamental insights of a novel connectivity index

open access: yesMain Group Metal Chemistry
Topological indices play a central role in mathematical chemistry for correlating structural features of molecular graphs with physicochemical properties.
Noreen Tahira, Salman Muhammad
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Molecular descriptor engineering for machine learning predictions in atmospheric science

open access: yes
Atmospheric organic compounds form complex mixtures, where new compounds may form via chemical reactions, increasing the number of unique molecular species and their complexity.
Lind, Linus
core  

Legitimate Utilization of Large Descriptor Pools for QSPR/QSAR Models

open access: yes, 2016
The use of large descriptor pools in multilinear QSAR/QSPR approaches has recently been increasingly criticized for their sensitivity to “chance correlations”.
Svetoslav Slavov (2407396)   +3 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

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