Results 131 to 140 of about 34,759 (340)
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
, 2013 Background While a large body of work exists on comparing and benchmarking of descriptors of molecular structures, a similar comparison of protein descriptor sets is lacking. Hence, in the current work a total of 13 different protein descriptor sets
Bender, A. +5 more
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Graph energy-A useful molecular structure-descriptor
, 2003 1309-1311The energy E(G) of a graph G is, by definition, equal to the sum of absolute values of the eigenvalues of G. The motivation for such a definition comes from molecular orbital theory, where E(G) pertains to the total π-electron energy of the ...
Gutrnan, Ivan +4 more
core
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Skematic representation of the molecular descriptor fNH5B in molecules 3 and 9 only.
Skematic representation of the molecular descriptor fNH5B in molecules 3 and 9 only.
Vijay H. Masand (13279344) +11 more
core +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Deconstructing adsorption variability: the prediction of spatial uncertainty in pollutant movement [PDF]
, 2008 Land pressures today and government policy-requires previously developed, 'brownfield' land to be brought back into beneficial use. The nature of these sites means that they may have been subject to some form of contamination from previous uses. The risk
Collins, John Philip
core
Complementing ultrafast shape recognition with an optical isomerism descriptor
, 2010 We introduce the mixed product of three vectors spanning four molecular locations as a descriptor of optical isomerism. This descriptor is very efficient as it does not require molecular superposition, and is very robust in discriminating between a given
Lafleur, K +5 more
core +1 more source
Genetic divergence of Anthurium affine germplasm using morphoagronomic and molecular descriptors
, 2021 Clara Yohana Maia +5 more
openalex +1 more source