Results 71 to 80 of about 3,260,181 (300)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
, 2020 Protective coatings have been shown to effectively suppress Mn ion dissolution from the spinel LiMn2O4 lithium-ion battery cathode by stabilizing the surface against undesired side reactions with the electrolyte.
Robert E. Warburton (8469045) +4 more
core +1 more source
Estimating the Laplacian Energy-Like Molecular Structure Descriptor [PDF]
, 2012 Lower and upper bounds for the Laplacian energy-like (LEL) molecular structure descriptor are obtained, better than those previously known. These bonds are in terms of number of vertices and edges of the underlying molecular graph and of graph complexity
Ivan Gutman, Gutman, Ivan
core +1 more source
Malaria Journal, 2021 Background Emergence of cross-resistance to current anti-malarial drugs has led to an urgent need for identification of potential compounds with novel modes of action and anti-malarial activity against the resistant strains.
Phuong Thuy Viet Nguyen +15 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
The influence of certain molecular descriptors of fecal elimination of angiotensin II receptor antagonists [PDF]
Archives of Biological Sciences, 2015 Angiotensin II receptor antagonists (ARBs) modulate the function of the renin-angiotensin-aldosterone system and are commonly prescribed antihypertensive drugs, especially in patients with renal failure.
Trbojević-Stanković Jasna B. +4 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Scalable Similarity Search for Molecular Descriptors [PDF]
, 2017 Similarity search over chemical compound databases is a fundamental task in the discovery and design of novel drug-like molecules. Such databases often encode molecules as non-negative integer vectors, called molecular descriptors, which represent rich information on various molecular properties.
Yasuo Tabei, Simon J. Puglisi
openaire +3 more sources
On Relationships of Eigenvalue–Based Topological Molecular Descriptors
Acta Chimica Slovenica, 2020 Three eigenvalue-based topological molecular descriptors are compared using several datasets of alkanes. Two of them are well-known and frequently employed in various QSPR/QSAR investigations, and third-one is a newly derived whose predictive potential is yet to be proven. The relations among them are found and discussed.
Redžepović I., Furtula, Boris
openaire +5 more sources
Vitae, 2005 La velocidad con que los bifenilos policlorados (PCBs) son eliminados en humanos, representada por sus períodos de vida media (t1/2), es de gran relevancia ambiental.
Isaura OSPINO M +2 more
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