Results 131 to 140 of about 1,982,601 (316)

Use of genetic methods for determining patterns and processes during marine biological invasions [PDF]

open access: yes, 2012
Invasive species are widely recognised as one of the major threats to marine biodiversity worldwide. With increasingly faster and more frequent transoceanic shipping, propagule pressure in the marine environment is likely to further increase, leading to ...
Smith, Kirsty Fiona
core  

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Loop-mediated isothermal amplification (LAMP) test for detection of Trypanosoma evansi strain B [PDF]

open access: yes, 2010
Camel Trypanosomiasis (Surra) is mainly caused by Trypanosoma evansi strains that express variable surface glycoprotein (VSG) RoTat 1.2 However, in Kenya a second causative strain that does not express RoTat 1.2 VSG (T. evansi type B) has been identified.
Njiru, Z.K.   +3 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

The role of molecular methods in the detection of pathogens in food [PDF]

open access: yes, 2004
The research described here addresses several issues associated with testing food samples for the presence of pathogens. Based on three different perspectives, the following major objectives are noted: (i) the use of molecular amplification methods to ...
Stevens, Kelly A.
core  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Desenvolvimento de procedimentos analíticos para a determinação de enxofre em carvão usando espectrometria de absorção molecular de alta resolução com fonte contínua em forno de grafite [PDF]

open access: yes, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Programa de Pós-Graduação em Química, Florianópolis, 2013.Análise direta de amostras sólidas é uma boa alternativa para a determinação de enxofre ...
Mior, Renata
core  

Molecular Assays for the Detection and Molecular Characterization of CTCs

open access: yes, 2016
Detection of Circulating Tumor Cells (CTC) in peripheral blood can serve as a “liquid biopsy” approach and has thus emerged lately as one of the hottest fields in cancer research. A variety of molecular assays are continuously been developed for CTC detection and molecular characterization.
Lianidou, E.S., Markou, A., Strati, A.
openaire   +2 more sources

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