Results 91 to 100 of about 1,774,415 (209)

Aptamer-based dual-enzyme, amplification-free biosensor integrating CRISPR-Cas12a and Exo III for sensitive detection of ATP

Sensing and Bio-Sensing Research
Adenosine triphosphate (ATP) plays a critical role in cellular energy metabolism, acting as the energy source for many biological reactions. Abnormal fluctuations in ATP levels are directly linked to various diseases such as malignancies, bacterial ...
Baolin Li, Yaxin Huang, Zixin Zhu, Min Zhong, Guangrong Li, Jinbo Liu   +5 more
doaj   +1 more source

Glioma through the looking GLASS: molecular evolution of diffuse gliomas and the Glioma Longitudinal Analysis Consortium. [PDF]

, 2018
Adult diffuse gliomas are a diverse group of brain neoplasms that inflict a high emotional toll on patients and their families. The Cancer Genome Atlas and similar projects have provided a comprehensive understanding of the somatic alterations and ...
GLASS Consortium
core  

Natural selection favoring more transmissible HIV detected in United States molecular transmission network. [PDF]

, 2019
HIV molecular epidemiology can identify clusters of individuals with elevated rates of HIV transmission. These variable transmission rates are primarily driven by host risk behavior; however, the effect of viral traits on variable transmission rates is ...
Campbell, Ellsworth, Heneine, Walid, Johnson, Jeffrey A, Oster, Alexandra M, Panneer, Nivedha, Saduvala, Neeraja, Switzer, William M, Wertheim, Joel O, Zhang, Chenhua   +8 more
core  

Mobile genetic elements encoding antibiotic resistance genes and virulence genes in Klebsiella pneumoniae: important pathways for the acquisition of virulence and resistance

Frontiers in Microbiology
Klebsiella pneumoniae is an opportunistic pathogen primarily associated with nosocomial infections, characterized by a propensity for multi-drug resistance and the potential evolution into hypervirulent strains.
Bin Han, Bin Han, Bin Han, Bin Han, Chunlin Feng, Chunlin Feng, Chunlin Feng, Yuan Jiang, Yuan Jiang, Yuan Jiang, Caihong Ye, Caihong Ye, Caihong Ye, Yueshuai Wei, Yueshuai Wei, Yueshuai Wei, Jinbo Liu, Jinbo Liu, Jinbo Liu, Jinbo Liu, Zhangrui Zeng, Zhangrui Zeng, Zhangrui Zeng   +22 more
doaj   +1 more source

Optical imaging for brown or beige adipose tissue

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Currently, one in three adults worldwide may be obese or overweight. Obesity is characterized by an excess of energy‐storing white fat. An ingenious and sought‐after strategy against obesity is to activate energy‐consuming beige fat, which is converted ...
Jiamin Liu, Linjie Ni, Minmin Peng, Yiying Liang, Chan Lu, Hanying Zheng, Zicheng Huang, Jinde Zhang, Ronghe Chen   +8 more
doaj   +1 more source

Identification of novel genes involved in gastric carcinogenesis by suppression subtractive hybridization [PDF]

, 2015
Gastric cancer (GC) is one of the most common and life-threatening types of malignancies. Identification of the differentially expressed genes in GC is one of the best approaches for establishing new diagnostic and therapeutic targets. Furthermore, these
Ebrahimifard, F., Mottaghi-Dastjerdi, N., Roshandel, G., Sepehrizadeh, Z., Setayesh, N., Soltany-Rezaee-Rad, M.   +5 more
core  

Hypoxia-triggered ERRα acetylation enhanced its oncogenic role and promoted progression of renal cell carcinoma by coordinating autophagosome-lysosome fusion

Cell Death and Disease
Estrogen-related receptor α (ERRα) is dysregulated in many types of cancer and exhibits oncogenic activity by promoting tumorigenesis and metastasis of cancer cells.
Chun Feng, Demin Kong, Binghua Tong, Yonghui Liang, Fuyi Xu, Yangyang Yang, Yingying Wu, Xiaodong Chi, Pengfei Wei, Yang Yang, Guilong Zhang, Geng Tian, Zhaowei Xu   +12 more
doaj   +1 more source

Clinical evaluation of two pathogen enrichment approaches for next-generation sequencing in the diagnosis of lower respiratory tract infections

Microbiology Spectrum
The underdevelopment of microbiological tests has contributed to diagnostic delay and inappropriate use of antibiotics in patients with lower respiratory tract infections, which is ranked as the seventh leading cause of death globally.
Xiao Lei, Xiumei Xu, Chao Liu, Lipeng Zhong, Shupeng Yin, Biaoxian Li, Ling Cao, Zhiting Xie, Jing Li, Xuan Zhang, Yaping Guo, Liang Zhang, Haiyan Lin, Sufeng Zhang, Chengsheng Zhang, Tian Gong   +15 more
doaj   +1 more source

Self‐assembly multifunctional DNA tetrahedron for efficient elimination of antibiotic‐resistant bacteria

Aggregate
Antibiotic resistance is a major challenge in the clinical treatment of bacterial infectious diseases. Herein, we constructed a multifunctional DNA nanoplatform as a versatile carrier for bacteria‐specific delivery of clinical antibiotic ciprofloxacin ...
Tiantian Wu, Yu Fu, Shuang Guo, Yanqiang Shi, Yuxin Zhang, Zhijin Fan, Bin Yang, Baoquan Ding, Yuhui Liao   +8 more
doaj   +1 more source

The role of molecular biology in diagnosis and follow-up in Barrett’s Esophagus [PDF]

, 2018
Geboes, Karen, Hoorens, Anne
core   +2 more sources