Results 81 to 90 of about 1,774,415 (209)

The Molecular Pathology of Prion Diseases [PDF]

, 2004
Prion diseases, or transmissible spongiform encephalopathies (TSEs), are a group of invariably fatal neurodegenerative disorders. Uniquely, they may present as sporadic, inherited, or infectious forms, all of which involve conversion of the normal ...
Herms, Jochen, Kretzschmar, Hans A., Vassallo, Neville   +2 more
core  

[Molecular diagnosis of tuberculosis].

Revue des maladies respiratoires, 2020
Tuberculosis is caused by the M. tuberculosis complex. Its slow growth delays the bacteriological diagnosis based on phenotypic tests. Molecular biology has significantly reduced this delay, notably thanks to the deployment of the Xpert® MTB/RIF test (Cepheid), which detects the M. tuberculosis complex and rifampicin resistance in 2hours.
Morel, Florence, Jaffré, Jérémy, Sougakoff, Wladimir, Aubry, Alexandra, Véziris, Nicolas   +4 more
openaire   +2 more sources

Molecular Diagnosis of Burkitt's Lymphoma

New England Journal of Medicine, 2006
The distinction between Burkitt's lymphoma and diffuse large-B-cell lymphoma is crucial because these two types of lymphoma require different treatments. We examined whether gene-expression profiling could reliably distinguish Burkitt's lymphoma from diffuse large-B-cell lymphoma.Tumor-biopsy specimens from 303 patients with aggressive lymphomas were ...
Dave, Sandeep S., Fu, Kai, Wright, George W., Lam, Lloyd T., Kluin, Philip, Boerma, Evert-Jan, Greiner, Timothy, Weisenburger, Dennis D., Rosenwald, Andreas, Ott, German, Müller-Hermelink, Hans-Konrad, Gascoyne, Randy D., Delabie, Jan, Rimsza, Lisa M., Braziel, Rita M., Grogan, Thomas M., Campo, Elias, Jaffe, Elaine S., Dave, Bhavana J., Sanger, Warren, Bast, M, Vose, Julie M., Armitage, James O., Connors, Joseph M., Smeland, Erlend B., Kvaloy, Stein, Holte, Harald, Fisher, Richard I., Miller, Thomas P., Montserrat, Emilio, Wilson, Wyndham H., Bahl, Manisha, Zhao, Hong, Yang, Liming, Powell, John, Simon, Richard, Chan, Wing C., Staudt, Louis M.   +37 more
openaire   +5 more sources

METTL3/IGF2BP2-Mediated m6A RNA Methylation Drives Alveolar Macrophage-Dependent Neutrophil Recruitment in Cigarette Smoke-Induced COPD

Journal of Inflammation Research
Andi Lin,1,* Jian Wang,2,* Lixing Wang,3 Yaping Zhang3,4 1The Second Clinical Medical College of Fujian Medical University, Quanzhou, Fujian, 362000, People’s Republic of China; 2Department of Pathology, The Second Affiliated Hospital of ...
Lin A, Wang J, Wang L, Zhang Y
doaj  

Molecular diagnosis of deafness

AUDIOLOGY JAPAN, 2011
Despite advances in discovery of deafness genes, clinical application still entails difficulties because of the genetic heterogeneity of deafness. In order to establish strategy for clinical application, we reviewed the genes responsible for hearing loss patients in Japan (Usami S et al; Acta Otolaryngol 128: 446-454, 2008), and discussed diagnostic ...
openaire   +4 more sources

Rapid Detection of Rongalite via a Sandwich Lateral Flow Strip Assay Using a Pair of Aptamers

Nanoscale Research Letters, 2018
A sandwich lateral flow strip assay (LFSA) using a couple of aptamers functionalized with gold nanoparticles (AuNPs) was designed to assess the presence of rongalite in agrifood products.
Jie Li, Le Jing, Yuzhu Song, Jinyang Zhang, Qiang Chen, Binghui Wang, Xueshan Xia, Qinqin Han   +7 more
doaj   +1 more source

Intelligent bacteria‐targeting ZIF‐8 composite for fluorescence imaging‐guided photodynamic therapy of drug‐resistant superbug infections and burn wound healing

Exploration
Infected burn wounds are characterized by persistent drug‐resistant bacterial infection coupled with an inflammatory response, impeding the wound‐healing process.
Xiaoxue Li, Wei Wang, Qiuxia Gao, Shanshan Lai, Yan Liu, Sitong Zhou, Yan Yan, Jie Zhang, Huanhuan Wang, Jiamei Wang, Yi Feng, Ronghua Yang, Jianyu Su, Bin Li, Yuhui Liao   +14 more
doaj   +1 more source

Short- and long-term glycemic effects of pasireotide in patients with acromegaly: a comprehensive case study with review of literature

Endocrine Journal
Pasireotide (PAS), a multireceptor somatostatin analog, has been demonstrated to effectively control hormone levels, including those of growth hormone (GH) and insulin-like growth factor 1 (IGF-1), in patients with acromegaly.
Yuki Taki, Takashi Kono, Tatsuma Matsuda, Ryunosuke Kozu, Masanori Fujimoto, Ikki Sakuma, Naoko Hashimoto, Kentaro Horiguchi, Yoshinori Higuchi, Tomoaki Tanaka   +9 more
doaj   +1 more source

Molecular diagnosis.

Canadian family physician Medecin de famille canadien, 2013
Recombinant DNA technology, one of the major controversial areas of biological research in the late 1970s, is now rapidly providing new avenues for diagnosis and treatment. With the early recognition that extensive DNA variation exists in human populations, molecular genetic diagnosis of a variety of common hereditary diseases has become a reality ...
openaire   +1 more source

CircRNF10 sequestrates β-catenin by a dual regulatory circuit of direct degradation and a miR-1275/DKK3-mediated inhibition in driver gene- negative lung adenocarcinoma

Molecular Cancer
Background Circular RNAs (circRNAs) exert critical regulatory functions in tumor biology by modulating pathways associated with oncogenesis or tumor suppression.
Xiaohua Situ, Xinwei Wang, Xiting Liao, Xiaoxuan Zhang, Sicheng Chen, Fei Fang, Lihong Wei, Peng Wu, Zhiyu Liu, Honglei Chen, Kejing Tang, Lihong Bai, Zunfu Ke   +12 more
doaj   +1 more source