Results 171 to 180 of about 7,339,385 (306)

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

CRISPR-Cas9 Therapeutics in Early Clinical Development: Delivery and Molecular Diagnostics. [PDF]

Cells
Rutkowska A, Strózik T, Wasiak T, Ciunowicz D, Kapelan N, Szczepaniak N, Sosnowski J, Goślińska W, Bartkowiak J, Budny-Lewandowska A, Antończyk P, Markiewicz M, Gustaw P, Filiks K, Jaskólska M, Stoczyńska-Fidelus E.   +15 more
europepmc   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Rapid Molecular Diagnostics for Bloodstream Infection in Patients with Chronic Kidney Disease. [PDF]

Diagnostics (Basel)
Elbehiry A, Marzouk E, Abalkhail A, Anagreyyah S, Almalki A, Alazwari N, Ramza H, Alsolami A, Alghamdi A.   +8 more
europepmc   +1 more source

De novo synthesis of short‐chain aldehydes and hydrocarbons secreted by the brown marmorated stink bug Halyomorpha halys

FEBS Open Bio, EarlyView.
The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley   +1 more source

Correction to: the role of metabolomics in hepatocellular carcinoma

Egyptian Liver Journal, 2021
Ashraf Khalil, Ashraf Elfert, Samar Ghanem, Marwa Helal, Shymaa Abdelsattar, Gamalate Elgedawy, Manar Obada, Mohamed Abdel-Samiee, Hala El-Said   +8 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Preparing Europe for imported Andes virus: the role of rapid serology and molecular diagnostics. [PDF]

Lancet Reg Health Eur
Velavan TP, Schmidt-Chanasit J.
europepmc   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source

Towards molecular diagnostics of parental alienation. [PDF]

Cell Mol Life Sci
Kamyshnyi O, Kamyshna I, Petakh P, Halabitska I, Bjoras M, Oksenych V, Schoving MP, Kainov DE.   +7 more
europepmc   +1 more source