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Prokaryotic Argonautes for in vivo biotechnology and molecular diagnostics.
Trends in Biotechnology, 2023Prokaryotic Argonautes (pAgos) are an emerging class of programmable endonucleases that are believed to be more flexible than existing CRISPR-Cas systems and have significant potential for biotechnology.
Brett A. Graver +2 more
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CRISPR-Based Precision Molecular Diagnostics for Disease Detection and Surveillance.
ACS Applied Bio Materials, 2023Sensitive, rapid, and portable molecular diagnostics is the future of disease surveillance, containment, and therapy. The recent SARS-CoV-2 pandemic has reminded us of the vulnerability of lives from ever-evolving pathogens.
A. Kulkarni +4 more
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Plasmon-Based Colorimetric Nanosensors for Ultrasensitive Molecular Diagnostics
ACS Sensors, 2017Longhua Tang, Jinghong Li
exaly +2 more sources
Engineering gold nanoparticles for molecular diagnostics and biosensing.
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 2022Advances in nanotechnology and medical science have spurred the development of engineered nanomaterials and nanoparticles with particular focus on their applications in biomedicine.
Beatriz Oliveira +3 more
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Molecular diagnostics in transplantation
Nature Reviews Nephrology, 2010The past few decades are characterized by an explosive evolution of genetics and molecular cell biology. Advances in chemistry and engineering have enabled increased data throughput, permitting the study of complete sets of molecules with increasing speed and accuracy using techniques such as genomics, transcriptomics, proteomics, and metabolomics ...
Maarten, Naesens, Minnie M, Sarwal
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Molecular diagnostics for haemoglobinopathies
Expert Opinion on Medical Diagnostics, 2010The globin gene mutations have been used as a prototype for the development of many techniques of mutation detection for > 30 years, and consequently there have been numerous PCR-based methods described that can be used for the molecular diagnosis of the haemoglobinopathies.This review describes the most commonly used current methods for the detection ...
John, Old, Shirley, Henderson
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ACS Nano
Molecular diagnostics (MD) is widely employed in multiple scientific disciplines, such as oncology, pathogen detection, forensic investigations, and the pharmaceutical industry.
Namhyun Choi, S. Schlücker
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Molecular diagnostics (MD) is widely employed in multiple scientific disciplines, such as oncology, pathogen detection, forensic investigations, and the pharmaceutical industry.
Namhyun Choi, S. Schlücker
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Molecular diagnostics for tuberculosis
Pathology, 2015The phenotypic methods of smear microscopy, culture and indirect drug susceptibility testing (DST) remain the 'gold standard' diagnostics for tuberculosis (TB) in 2015. However, this review demonstrates that genotypic methods are in the ascendancy. Current-generation nucleic acid amplification tests (NAATs) are important supplementary tests for the ...
Noor, K., Shephard, L., Bastian, I.
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Journal of Molecular Medicine, 1997
Nucleic acid technology has assumed an essential role in various areas of in vitro diagnosis. Its major applications include the genomic characterization of mutations and polymorphisms, amplification of nucleic acids by the polymerase chain reaction, analysis of gene expression patterns at the mRNA level, specific detection of mutant proteins, and ...
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Nucleic acid technology has assumed an essential role in various areas of in vitro diagnosis. Its major applications include the genomic characterization of mutations and polymorphisms, amplification of nucleic acids by the polymerase chain reaction, analysis of gene expression patterns at the mRNA level, specific detection of mutant proteins, and ...
openaire +2 more sources
The CRISPR-Cas system in molecular diagnostics.
Clinica chimica acta; international journal of clinical chemistryRobust, sensitive, and rapid molecular detection tools are essential prerequisites for disease diagnosis and epidemiological control. However, the current mainstream tests necessitate expensive equipment and specialized operators, impeding the ...
Rao Song +3 more
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