Results 271 to 280 of about 7,339,385 (306)

Nucleic Acid Aptamers for Molecular Diagnostics and Therapeutics: Advances and Perspectives.

Angewandte Chemie, 2020
The advent of SELEX (Systematic Evolution of Ligands by Exponential enrichment) technology has shown the ability to evolve artificial ligands with affinity and specificity able to meet growing clinical demand for probes that can, for example, distinguish
Long Li, Shu-juan Xu, He Yan, Xiaowei Li, H. S. Yazd, Xiang Li, Tong Huang, Cheng Cui, Jian-hui Jiang, W. Tan   +9 more
semanticscholar   +1 more source

Nanoparticles in Molecular Diagnostics

2011
The aim of this chapter is to provide an overview of the available and emerging molecular diagnostic methods that take advantage of the unique nanoscale properties of nanoparticles (NPs) to increase the sensitivity, detection capabilities, ease of operation, and portability of the biodetection assemblies.
Pedro V, Baptista, Gonçalo, Doria, Pedro, Quaresma, Miguel, Cavadas, Cristina S, Neves, Inês, Gomes, Peter, Eaton, Eulália, Pereira, Ricardo, Franco   +8 more
openaire   +2 more sources

Nanoplasmonic On-Chip PCR for Rapid Precision Molecular Diagnostics.

ACS Applied Materials and Interfaces, 2020
Emerging molecular diagnosis requires ultrafast polymerase chain reaction (PCR) on chip for rapid precise detection of infectious diseases in the point-of-care test. Here we report nanoplasmonic on-chip PCR for rapid precision molecular diagnostics.
Youngseop Lee, Byoung-Hoon Kang, Minhee Kang, D. Chung, G. Yi, Luke P. Lee, K. Jeong   +6 more
semanticscholar   +1 more source

Molecular diagnostics

Nature Reviews Drug Discovery, 2009
exaly   +2 more sources

Molecular Diagnostics in Genodermatoses

Seminars in Cutaneous Medicine and Surgery, 2012
In recent years, there has been tremendous progress in elucidating the molecular bases of genodermatoses. The interface between genetics and dermatology has broadened with the identification of "new" heritable disorders, improved recognition of phenotypic spectrums, and integration of molecular and clinical data to simplify disease categorization and ...
openaire   +2 more sources

Pitfalls in molecular diagnostics

Seminars in Diagnostic Pathology, 2019
Molecular diagnostic techniques are part of the ancillary arsenal of anatomic pathologists. Advances in technology and knowledge regarding disease pathogenesis, tumorigenesis, and immune function contribute to the development of these assays. However, each technique, if applied incorrectly or in ignorance, can lead to difficulties in execution or ...
Lulu, Sun, John D, Pfeifer
openaire   +2 more sources

Molecular diagnostics in melanoma

Journal of the American Academy of Dermatology, 2005
Molecular pathology is rapidly evolving, featuring continuous technologic improvements that offer novel clinical opportunities for the recognition of disease predisposition, for identifying sub-clinical disease, for more accurate diagnosis, for selecting efficacious and non-toxic therapy, and for monitoring of disease outcome.
J Andrew, Carlson, Jeffery S, Ross, Andrzej, Slominski, Gerald, Linette, Judith, Mysliborski, Jerome, Hill, Martin, Mihm   +6 more
openaire   +2 more sources

Molecular diagnostics by microelectronic microchips

Expert Review of Molecular Diagnostics, 2005
Molecular diagnostics is being revolutionized by the development of highly advanced technologies for DNA and RNA testing. One of the most important challenges is the integration of microelectronics to microchip-based nucleic acid technologies. The specific characteristics of these microsystems make the miniaturization and automation of any step of a ...
FERRARI , MAURIZIO, Cremonesi L, Bonini PA, Stenirri S, Foglieni B.   +4 more
openaire   +3 more sources

Molecular Tools for Diagnostics

2011
More than 4,000 nematode species are parasites of plants, some of which are responsible for considerable yield and quality losses in many important agronomical plants. Because of their small size, the homogeneity of their morphological characters, and their soil distribution, most plant-parasitic nematodes (PPNs) are difficult to detect and identify ...
Castagnone-Sereno, Philippe, Skantar, Andrea, Robertson, Lee   +2 more
openaire   +3 more sources

Molecular Diagnostics in China

Clinical Chemistry and Laboratory Medicine, 2001
Molecular diagnostics is changing the face of clinical laboratories and laboratory medicine. The case of China is no exception. In the present paper, a brief description on this promising discipline is given first, followed by an overview of the development of molecular diagnostics in China. Work done in the author's own laboratory is introduced in the
openaire   +2 more sources