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Nanoparticles in Molecular Diagnostics
2011The aim of this chapter is to provide an overview of the available and emerging molecular diagnostic methods that take advantage of the unique nanoscale properties of nanoparticles (NPs) to increase the sensitivity, detection capabilities, ease of operation, and portability of the biodetection assemblies.
Pedro V, Baptista +8 more
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Molecular diagnostics for tuberculosis
Pathology, 2015The phenotypic methods of smear microscopy, culture and indirect drug susceptibility testing (DST) remain the 'gold standard' diagnostics for tuberculosis (TB) in 2015. However, this review demonstrates that genotypic methods are in the ascendancy. Current-generation nucleic acid amplification tests (NAATs) are important supplementary tests for the ...
Noor, K., Shephard, L., Bastian, I.
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Journal of Molecular Medicine, 1997
Nucleic acid technology has assumed an essential role in various areas of in vitro diagnosis. Its major applications include the genomic characterization of mutations and polymorphisms, amplification of nucleic acids by the polymerase chain reaction, analysis of gene expression patterns at the mRNA level, specific detection of mutant proteins, and ...
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Nucleic acid technology has assumed an essential role in various areas of in vitro diagnosis. Its major applications include the genomic characterization of mutations and polymorphisms, amplification of nucleic acids by the polymerase chain reaction, analysis of gene expression patterns at the mRNA level, specific detection of mutant proteins, and ...
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Molecular diagnostics in melanoma
Journal of the American Academy of Dermatology, 2005Molecular pathology is rapidly evolving, featuring continuous technologic improvements that offer novel clinical opportunities for the recognition of disease predisposition, for identifying sub-clinical disease, for more accurate diagnosis, for selecting efficacious and non-toxic therapy, and for monitoring of disease outcome.
J Andrew, Carlson +6 more
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Molecular Diagnostics in Genodermatoses
Seminars in Cutaneous Medicine and Surgery, 2012In recent years, there has been tremendous progress in elucidating the molecular bases of genodermatoses. The interface between genetics and dermatology has broadened with the identification of "new" heritable disorders, improved recognition of phenotypic spectrums, and integration of molecular and clinical data to simplify disease categorization and ...
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Pitfalls in molecular diagnostics
Seminars in Diagnostic Pathology, 2019Molecular diagnostic techniques are part of the ancillary arsenal of anatomic pathologists. Advances in technology and knowledge regarding disease pathogenesis, tumorigenesis, and immune function contribute to the development of these assays. However, each technique, if applied incorrectly or in ignorance, can lead to difficulties in execution or ...
Lulu, Sun, John D, Pfeifer
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Molecular diagnostics by microelectronic microchips
Expert Review of Molecular Diagnostics, 2005Molecular diagnostics is being revolutionized by the development of highly advanced technologies for DNA and RNA testing. One of the most important challenges is the integration of microelectronics to microchip-based nucleic acid technologies. The specific characteristics of these microsystems make the miniaturization and automation of any step of a ...
FERRARI , MAURIZIO +4 more
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Molecular Tools for Diagnostics
2011More than 4,000 nematode species are parasites of plants, some of which are responsible for considerable yield and quality losses in many important agronomical plants. Because of their small size, the homogeneity of their morphological characters, and their soil distribution, most plant-parasitic nematodes (PPNs) are difficult to detect and identify ...
Castagnone-Sereno, Philippe +2 more
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Molecular Diagnostics in China
Clinical Chemistry and Laboratory Medicine, 2001Molecular diagnostics is changing the face of clinical laboratories and laboratory medicine. The case of China is no exception. In the present paper, a brief description on this promising discipline is given first, followed by an overview of the development of molecular diagnostics in China. Work done in the author's own laboratory is introduced in the
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Molecular diagnostics in dermatology
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, 2022openaire +3 more sources