Results 161 to 170 of about 4,185,495 (377)

Ultrasensitive Detection of FKBP12 Using a Synthetic Receptor‐Functionalized QCM Nanoplatform

Advanced Sensor Research, EarlyView.
A reusable nanosensor platform for ultralow FKBP12 detection in physiological fluids is presented. Combining a gold‐coated QCM with a custom‐designed receptor in a self‐assembled monolayer, the device achieves picomolar sensitivity and high selectivity.
Martina Tozzetti, Maria Raffaella Martina, Giacomo Lucchesi, Kristian Vasa, Ahtsham Ishaq, Laura Marsili, Piero Procacci, Stefano Menichetti, Gabriella Caminati   +8 more
wiley   +1 more source

Implicit Ligand Theory: Rigorous Binding Free Energies and Thermodynamic Expectations from Molecular Docking

, 2012
A rigorous formalism for estimating noncovalent binding free energies and thermodynamic expectations from calculations in which receptor configurations are sampled independently from the ligand is derived.
Minh, David D. L.
core   +1 more source

Molecular modeling of G-protein coupled receptor kinase 2: Docking and biochemical evaluation of inhibitors [PDF]

, 2000
Matthias U. Kassack, Petra Högger, Daniel A. Gschwend, Kimihiko Kameyama, Tatsuya Haga, Richard C. Graul, Wolfgang Sadée   +6 more
openalex   +1 more source

Nanocrystalline Cellulose from the Solitary Tunicate Phallusia Mammillata, a Valuable Nanocellulose Precursor

Advanced Sustainable Systems, EarlyView.
This study explores the potential of locally harvested Phallusia mammillata, a tunicate usually discarded as waste from mussles farming as a viable source for producing various high‐grade cellulose derivatives in the form of nanofibrils (NFC) and nanocrystals (CNC). Abstract Ascidians are ubiquitous filter‐feeding marine invertebrates, the only animals
Andrea Riccioni, Alessia Famengo, Naida El Habra, Loriano Ballarin, Lucia Manni, Annj Zamuner, Elisabetta Schievano   +6 more
wiley   +1 more source

Molecular motors: Kinesin’s dynamically dockable neck [PDF]

, 2000
Robert A. Cross
openalex   +1 more source

Fluorescent Chitosan Hydrogels Based on Biomass‐Derived Carbon Dots for Toxic Aromatic Detection

Advanced Sustainable Systems, EarlyView.
Carbon dots made from food waste via a microwave–ultrasound method show strong, pH‐stable fluorescence. Thermal pretreatment enhances their optical properties. Incorporated into chitosan hydrogels, these dots form reusable sensors for detecting aromatic pollutants in water.
Imane Haddadou, Patrick Brisebois, Claudiane M. Ouellet‐Plamondon, Daniele Benetti, Federico Rosei   +4 more
wiley   +1 more source

Lessons in Molecular Recognition: The Effects of Ligand and Protein Flexibility on Molecular Docking Accuracy [PDF]

, 2003
Jon A. Erickson, Mehran Jalaie, D. H. Robertson, Richard A. Lewis, Michal Vieth   +4 more
openalex   +1 more source

Elevated Histone Lactylation Mediates Ferroptosis Resistance in Endometriosis Through the METTL3‐Regulated HIF1A/HMOX1 Signaling Pathway

Advanced Science, EarlyView.
This study reveals that histone lactylation, a modification derived from lactate, plays a crucial role in ferroptosis resistance in ectopic endometrial stromal cells. This resistance is mediated via the HIF1A/HMOX1 pathway regulated by METTL3. In vivo, a combination of 2‐DG and erastin shows promise as an effective treatment for endometriosis ...
Zongwen Liang, Jinming Liu, Yanling Gou, Honglin Wang, Zhi Li, Yingying Cao, Huiyan Zhang, Ruru Bai, Zongfeng Zhang   +8 more
wiley   +1 more source

Molecular docking of substrates and inhibitors in the catalytic site of CYP6B1, an insect cytochrome P450 monooxygenase [PDF]

, 2003
Jérôme Baudry, W. Li, Lele Pan, May R. Berenbaum, M. A. Schuler   +4 more
openalex   +1 more source

NOX2 Contributes to High‐Frequency Outer Hair Cell Vulnerability in the Cochlea

Advanced Science, EarlyView.
This study first identifies NOX2 as a differentially expressed gene related to oxidative damage in the apical and basal turns through single‐cell RNA sequencing. NOX2 gene knockout mitigates OHCs damage caused by neomycin and noise and enhances Nrf2 expression and nuclear translocation.
Meihao Qi, Zejun Gao, Yang Qiu, Renfeng Wang, Keyong Tian, Bo Yue, Xinyu Zhang, Peng Zhang, Ziqi Wu, Qingwen Zhu, Zhenzhen Liu, Zhuoyao Ma, Xueying Zhou, Yu Han, Jun Chen, Jianhua Qiu, DingJun Zha   +16 more
wiley   +1 more source