Results 231 to 240 of about 4,323,150 (379)

Structural analysis of catalase from two Musa accessions, FHIA18 and Williams, and from Ravenala madagascariensis [PDF]

, 2008
Jaufeerally-Fakim, Y., Khroyratty, S.S.S., Souza, M.T.   +2 more
core   +1 more source

Discussion on the mechanism of Danggui Sini decoction in treating diabetic foot based on network pharmacology and molecular docking and verification of the curative effect by meta-analysis [PDF]

Xiyu Ni, Huhe Bao, Jiaxing Guo, Deer Li, Lihang Wang, Wanyin Zhang, Guanwen Sun   +6 more
openalex   +1 more source

HRS Degradation‐Induced Nicotinamide Deficiency in Placental Extracellular Vesicles Triggers Preeclampsia by Disrupting Maternal‐Fetal Immune Homeostasis

Advanced Science, EarlyView.
This study shows that lower NAM levels in PE‐derived pEVs correlate with disease severity. NAM‐deficient pEVs reduce Th1 and Th17 inhibition, leading to PE‐like symptoms. NAM in pEVs inhibits Th1 via SIRT1 and Th17 via macrophages. Reduced NAM in PE‐EVs is due to decreased HRS expression in trophoblasts, resulting from elevated HSP27.
Haiyi Fei, Yuhan Lin, Xiu Liu, Xiaohong Zhu, Xiaowen Lu, Zhan Shi, Fan Jia, Shiqian Xu, Ling Fang, Lingling Jiang, Songying Zhang   +10 more
wiley   +1 more source

Electrochemical detection of atrazine using a zinc methylimidazolate framework with molecular docking insights. [PDF]

Sci Rep
Singh S, N P, Varshney R, Panchal A, Ramamurthy PC, Singh J, Shehata N.   +6 more
europepmc   +1 more source

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

Advanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang, Linghua Zeng, Kunkun Zou, Keying Lin, Fangting Yao, Jinglun Song, Shumeng Zhang, Hanshu Feng, Zhichao Yang, Chunlei Wang, Hongtao Diao, Xue Kong, Tengfei Pan, Joonki Kim, Tianqi Duo, Linqiang Li, Yu Bian   +16 more
wiley   +1 more source

Special Issue: "Therapeutic Potential of Natural Compounds: Insights into Mechanisms, Molecular Docking, and Biological Activities". [PDF]

Int J Mol Sci
Hałasa R.
europepmc   +1 more source

Molecular Docking of Endolysins for Studying Peptidoglycan Binding Mechanism [PDF]

Arina G. Arakelian, Gennady N. Chuev, T. N. Mamedov   +2 more
openalex   +1 more source

Molecular Docking Studies [PDF]

, 2018
openaire   +1 more source

Investigating Mitochondrial Viscosity in Ferroptosis‐Mediated Drug‐Induced Liver Injury using a Double‐Targeted Strategy

Advanced Science, EarlyView.
Utilizing a mitochondrial double‐targeted strategy, a novel near‐infrared fluorescent probe (FTZ‐2) is established for monitoring viscosity variations in ferroptosis‐mediated drug‐induced liver injury. In summary, this work provided a practical strategy for the early diagnosis and evaluation of liver injury.
Yongqing Zhou, Yan Wang, Bing Huang, Hosoowi Lee, Mei Yan, Juyoung Yoon   +5 more
wiley   +1 more source

Network Pharmacology and Molecular Docking Elucidate the Mechanism of Phillyrin in Colorectal Cancer. [PDF]

Food Sci Nutr
Hu ZJ, Lv GJ, Dong WS, Zheng F, Yan PH, Yu SL, He DN, Liu BY, Gao YY, Su DY, Guo YY, Bai YH, Zhu HY.   +12 more
europepmc   +1 more source