Results 301 to 310 of about 4,190,416 (396)

Monoamine Neurotransmitters as Substrates for Novel Tick Sulfotransferases, Homology Modeling, Molecular Docking, and Enzyme Kinetics [PDF]

, 2010
Emine Yalçın, Hubert Stangl, Sivakamasundari Pichu, Thomas N. Mather, Robert J. King   +4 more
openalex   +1 more source

Genome‐Wide Association Studies Reveal the Genetic Architecture of Ionomic Variation in Grains of Tartary Buckwheat

Advanced Science, Volume 12, Issue 17, May 8, 2025.
In this study, variation and genetic basis of ionome among Tartary buckwheat population are investigated, illuminating their significance in the domestication and diversification of Tartary buckwheat. And three genes (FtACA13 for Na content, FtYPQ1 for Zn content, FtNHX2 for As content) are identified with the dominant haplotypes and functional ...
Zhirong Wang, Yuqi He, Mengyu Zhao, Xiang‐Qian Liu, Hao Lin, Yaliang Shi, Kaixuan Zhang, Guijie Lei, Dili Lai, Tong Liu, Xiaoyang Peng, Jiayue He, Wei Li, Xiangru Wang, Sun‐Hee Woo, Muriel Quinet, Alisdair R. Fernie, Xin‐Yuan Huang, Meiliang Zhou   +18 more
wiley   +1 more source

Spectroscopic and molecular docking studies on binding interactions of camptothecin drugs with bovine serum albumin. [PDF]

Sci Rep
Wang Y, Li J, Li X, Gao B, Chen J, Song Y.   +5 more
europepmc   +1 more source

Fluorocurcumins as Cyclooxygenase-2 Inhibitor: Molecular Docking, Pharmacokinetics and Tissue Distribution in Mice

, 2009
Subhash Padhyé, Sanjeev Banerjee, Deepak Chavan, Shubhangini Pandye, K. Venkateswara Swamy, Shadan Ali, Jing Li, Q. Ping Dou, Fazlul H. Sarkar   +8 more
openalex   +2 more sources

Berberine is a Novel Mitochondrial Calcium Uniporter Inhibitor that Disrupts MCU‐EMRE Assembly

Advanced Science, Volume 12, Issue 17, May 8, 2025.
Berberine, a safe and FDA‐approved drug, is identified as a novel mitochondrial calcium uniporter (MCU) inhibitor. By disrupting MCU‐EMRE interaction, Berberine prevents mitochondrial calcium overload and protects against ischemia/reperfusion injury, offering a promising therapeutic strategy for diseases linked to mitochondrial calcium dysregulation ...
Haixin Zhao, Siqi Chen, Nian Cao, Wenjun Wu, Guangqin Liu, Jun Gao, Jiayi Chen, Ting Li, Dingyi Lu, Lingmin Zeng, Haizhen Zhu, Weina Zhang, Qing Xia, Teng Li, Tao Zhou, Xue‐Min Zhang, Ai‐Ling Li, Xin Pan   +17 more
wiley   +1 more source

Effects of Baicalin on Gout Based on Network Pharmacology, Molecular Docking, and in vitro Experiments. [PDF]

J Inflamm Res
Liu C, Liu W, Lu H, Fan Y, Wang A.
europepmc   +1 more source

DPImpute: A Genotype Imputation Framework for Ultra‐Low Coverage Whole‐Genome Sequencing and its Application in Genomic Selection

Advanced Science, Volume 12, Issue 16, April 24, 2025.
DPImpute is a two‐step pipeline that outperforms existing tools in whole‐genome SNP imputation, particularly under conditions of ultra‐low coverage sequencing, small sample sizes, and limited references. It enables precise imputation for single blastocyst cells, supporting genomic selection at the pre‐implantation stage.
Weigang Zheng, Wenlong Ma, Zhilong Chen, Chao Wang, Tao Sun, Wenjun Dong, Wenjing Zhang, Song Zhang, Zhonglin Tang, Kui Li, Yunxiang Zhao, Yuwen Liu   +11 more
wiley   +1 more source

Deep Learning Combined with Quantitative Structure‒Activity Relationship Accelerates De Novo Design of Antifungal Peptides

Advanced Science, Volume 12, Issue 13, April 3, 2025.
Drug resistance remains a serious threat to human health and the planet's ecology. Using deep learning integrated with quantitative structure‒activity relationship, 49 highly active antifungal peptides are de novo designed. In vitro and in vivo studies demonstrate these peptides' potential to minimize the risk of resistance development in pathogens ...
Kedong Yin, Ruifang Li, Shaojie Zhang, Yiqing Sun, Liang Huang, Mengwan Jiang, Degang Xu, Wen Xu   +7 more
wiley   +1 more source

Imperatorin's Effect on Myocardial Infarction Based on Network Pharmacology and Molecular Docking. [PDF]

Cardiovasc Ther
Zhang R, Wang P, Jin Y, Xie Q, Xiao P.
europepmc   +1 more source

YC‐4‐3, a Novel Glycogen Synthase Kinase 3β Inhibitor, Alleviates the Endoplasmic Reticulum Stress of Macrophages in Primary Immune Thrombocytopenia

Advanced Science, Volume 12, Issue 17, May 8, 2025.
A patented GSK‐3β inhibitor (GSK‐3βi), new benzothiazepinone compounds (BTZs), YC‐4‐3, can modulate the inflammatory status of macrophages in primary immune thrombocytopenia (ITP), and improve the thrombocytopenia in murine ITP models by directly interacting with endoplasmic reticulum (ER) stress response.
Pengcheng Xu, Lili Ji, Yanxia Zhan, Yang Ou, Xia Shao, Xibing Zhuang, Fanli Hua, Feng Li, Hao Chen, Yong Chu, Yunfeng Cheng   +10 more
wiley   +1 more source