Results 261 to 270 of about 8,193,792 (388)

Feasibility of Combining Biomolecular Conformational Sampling Techniques for Molecular Dynamics Simulation. [PDF]

J Comput Chem
Ikebe J, Kono H.
europepmc   +1 more source

Development of a personalized visualization and analysis tool to improve clinical care in complex multisystem diseases with application to scleroderma

Arthritis Care &Research, Accepted Article.
Background In complex diseases, it is challenging to assess a patient's disease state, trajectory, treatment exposures, and risk of multiple outcomes simultaneously, efficiently and at the point of care. Methods We developed an interactive patient‐level data visualization and analysis tool (VAT) that automates illustration of a scleroderma patient's ...
Ji Soo Kim, John Scott, Lauren Fisher, Lauren N. Smith, Willie Stewart, Adrianne Woods, Rob Smithwright, Diane Koher, Parastoo Aslanbeik, Aalok B. Shah, Brad Tibbils, Samantha I. Pitts, Ayse P. Gurses, Yushi Yang, Ana‐Maria Orbai, Antony Rosen, Laura K. Hummers, Scott L. Zeger, Ami A. Shah   +18 more
wiley   +1 more source

Molecular Dynamics of a Polymer Blend Model on a Solid Substrate. [PDF]

Molecules
Ayo-Ojo OE, Tsige M, Mola GT, Rotondo A, La Torre GL, Pellicane G.   +5 more
europepmc   +1 more source

Global and regional temporal changes in cross‐country inequalities of site‐specific osteoarthritis burden, 1990–2021

Arthritis Care &Research, Accepted Article.
Objective This study examined the global and regional temporal changes in cross‐country inequalities of site‐specific osteoarthritis (OA) burden from 1990 to 2021. Methods Age‐standardized years lived with disability rate for site‐specific OA across 204 countries/territories were obtained from the Global Burden of Diseases Study (GBD) 2021.
Haowei Chen, Lei Si, David J Hunter, Lei Zhang, Zhe‐Sheng Chen, Xiaomeng Wang, Vicky Duong, Zhounan Zhou, Peihua Cao, Han Cen, Su'an Tang, Tianyu Chen, Houjun Xue, Zhaohua Zhu, Changhai Ding   +14 more
wiley   +1 more source

Molecular Dynamics Simulations of a Putative Novel Mechanism for UCP1-Assisted FA Anion Transport. [PDF]

Acta Physiol (Oxf)
Vojvodić S, Roticiani G, Vazdar M, Pohl EE.   +3 more
europepmc   +1 more source

Structural analysis of a molten (Li-Na-K)Cl mixture of the eutectic composition by means of X-ray diffraction and molecular dynamics simulation.

, 1986
Akira Endoh, Toshio YAMAGUCHI, Isao Okada, Hitoshi Ohtaki   +3 more
openalex   +2 more sources

Hyperoxia Induced Alteration of Chromatin Structure in Human Bone Marrow Derived Primary Mesenchymal Stromal Cells

Advanced Biology, EarlyView.
Chromatin, which organizes DNA, changes its structure to adapt to stress like high oxygen levels (hyperoxia), which can damage cells. Researchers developed a technique to observe these changes and found variability in how different parts of chromatin remodel.
Lauren Monroe, Samantha Kaonis, Natalie Calahan, Neda Kabi, Soham Ghosh   +4 more
wiley   +1 more source

Dynamicasome-a molecular dynamics-guided and AI-driven pathogenicity prediction catalogue for all genetic mutations. [PDF]

Commun Biol
Islam NN, Coban MA, Fuller JM, Weber C, Chitale R, Jussila B, Brock TJ, Tao C, Caulfield TR.   +8 more
europepmc   +1 more source

Activation of NF‐κB Signaling by Optogenetic Clustering of IKKα and β

Advanced Biology, EarlyView.
This study presents an optogenetic approach for graded clustering of eGFP‐fused proteins using an eGFP‐specific nanobody and engineered Cryptochrome 2 variants. The method enables potent, reversible activation of NF‐κB signaling via endogenous pathways, as confirmed by RNA sequencing. This versatile system provides a spatially and temporally controlled
Alexandra Anna Maria Fischer, Markus Michael Kramer, Miguel Baños, Merlin Moritz Grimm, Manfred Fliegauf, Bodo Grimbacher, Gerald Radziwill, Sven Rahmann, Wilfried Weber   +8 more
wiley   +1 more source

Using Machine Learning to Analyze Molecular Dynamics Simulations of Biomolecules. [PDF]

J Phys Chem B
Brownless AR, Rheaume E, Kuo KM, Kamerlin SCL, Gumbart JC.   +4 more
europepmc   +1 more source