Results 81 to 90 of about 8,517,557 (393)

Dynamical importance of van der Waals saddle and excited potential surface in C(1D)+D2 complex-forming reaction

Nature Communications, 2017
It is commonly held that van der Waals wells are inevitable in chemical reactions. Here, the authors show that weak van der Waals forces in the entrance channel of a prototypical complex-forming reaction cause a van der Waals saddle instead, with ...
Zhitao Shen, Haitao Ma, Chunfang Zhang, Mingkai Fu, Yanan Wu, Wensheng Bian, Jianwei Cao   +6 more
doaj   +1 more source

Increased intracellular crowding during hyperosmotic stress

Scientific Reports, 2023
Hyperosmotic stress activates in live cells numerous processes and also promotes intracellular protein/RNA aggregation and phase separation. However, the time course and the extent of these changes remain largely uncharacterized.
Akira Kitamura, Sho Oasa, Haruka Kawaguchi, Misato Osaka, Vladana Vukojević, Masataka Kinjo   +5 more
doaj   +1 more source

Effective Sampling in the Configurational Space by the Multicanonical-Multioverlap Algorithm

, 2006
We propose a new generalized-ensemble algorithm, which we refer to as the multicanonical-multioverlap algorithm. By utilizing a non-Boltzmann weight factor, this method realizes a random walk in the multi-dimensional, energy-overlap space and explores ...
B. A. Berg, M. H. Quenouille, R. G. Miller, Satoru G. Itoh, Y. Sugita, Yuko Okamoto   +5 more
core   +1 more source

Statistical Properties of Fermionic Molecular Dynamics [PDF]

, 1995
Statistical properties of Fermionic Molecular Dynamics are studied. It is shown that, although the centroids of the single--particle wave--packets follow classical trajectories in the case of a harmonic oscillator potential, the equilibrium properties of
Feldmeier, Feldmeier, Feldmeier, H. Feldmeier, J. Schnack, Klauder, Ohnishi, Ohnishi, Ono, Ono, Ono, Pochodzalla, Schnack   +12 more
core   +2 more sources

Mitochondrial fatty acid oxidation is stimulated by red light irradiation

FEBS Letters, EarlyView.
Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera, Camille C. Caldeira da Silva, Maiza Von Dentz, Mauricio S. Baptista, Alicia J. Kowaltowski   +4 more
wiley   +1 more source

Label-free neuroimaging in vivo using synchronous angular scanning microscopy with single-scattering accumulation algorithm

Nature Communications, 2019
A major challenge of in vivo imaging is imaging deeper, including in turbid tissue. The authors report an adaptive optics based microscope that uses coherent single scattering signal to reduce sample-induced aberrations and enable fast deep-tissue ...
Moonseok Kim, Yonghyeon Jo, Jin Hee Hong, Suhyun Kim, Seokchan Yoon, Kyung-Deok Song, Sungsam Kang, Byunghak Lee, Guang Hoon Kim, Hae-Chul Park, Wonshik Choi   +10 more
doaj   +1 more source

Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1

FEBS Letters, EarlyView.
Tgl1, one of yeast sterol ester hydrolases, had been found on the lipid droplets where sterol esters are mainly stored. This study revealed that Tgl1 is transported into the vacuole depending on the ESCRT‐I–III complex, and that it exhibits intra‐vacuolar sterol ester hydrolase activity.
Takumi Nakatsuji, Kosuke Shiraishi, Chuqian Wang, Hiroya Yurimoto, Yasuyoshi Sakai, Masahide Oku   +5 more
wiley   +1 more source

Conformational dynamics of a single protein monitored for 24 hours at video rate [PDF]

, 2018
We use plasmon rulers to follow the conformational dynamics of a single protein for up to 24 h at a video rate. The plasmon ruler consists of two gold nanospheres connected by a single protein linker.
Ahijado-Guzmán, Rubén, Celiksoy, Sirin, Götz, Markus, Hugel, Thorsten, Prasad, Janak, Ratzke, Christoph, Ricken, Julia, Sönnichsen, Carsten, Tüting, Laura, Wegner, Seraphine V., Ye, Weixiang   +10 more
core   +3 more sources

TeraChem: A graphical processing unit‐accelerated electronic structure package for large‐scale ab initio molecular dynamics

WIREs Computational Molecular Science, 2020
TeraChem was born in 2008 with the goal of providing fast on‐the‐fly electronic structure calculations to facilitate ab initio molecular dynamics studies of large biochemical systems such as photoswitchable proteins and multichromophoric antenna ...
Stefan Seritan, Stefan Seritan, Christoph Bannwarth, Christoph Bannwarth, B. S. Fales, B. S. Fales, E. Hohenstein, E. Hohenstein, C. Isborn, Sara Kokkila-Schumacher, Xin Li, F. Liu, Nathan Luehr, James W. Snyder, Chenchen Song, Chenchen Song, A. Titov, Ivan S. Ufimtsev, Lee‐Ping Wang, T. Martínez, T. Martínez   +20 more
semanticscholar   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source