Results 81 to 90 of about 8,584,903 (389)

Coulomb Interactions via Local Dynamics: A Molecular--Dynamics Algorithm

open access: yes, 2004
We derive and describe in detail a recently proposed method for obtaining Coulomb interactions as the potential of mean force between charges which are dynamically coupled to a local electromagnetic field.
  +12 more
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Label-free neuroimaging in vivo using synchronous angular scanning microscopy with single-scattering accumulation algorithm

open access: yesNature Communications, 2019
A major challenge of in vivo imaging is imaging deeper, including in turbid tissue. The authors report an adaptive optics based microscope that uses coherent single scattering signal to reduce sample-induced aberrations and enable fast deep-tissue ...
Moonseok Kim   +10 more
doaj   +1 more source

Collective dynamics in phospholipid bilayers investigated by inelastic neutron scattering: Exploring the dynamics of biological membranes with neutrons

open access: yes, 2004
We present the first inelastic neutron scattering study of the short wavelength dynamics in a phospholipid bilayer. We show that inelastic neutron scattering using a triple-axis spectrometer at the high flux reactor of the ILL yields the necessary ...
C Ollinger   +10 more
core   +3 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Molecular dynamics

open access: yesThe Journal of Logic and Algebraic Programming, 2002
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Bergstra, J.A., Bethke, I.
openaire   +5 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Molecular dynamics simulations of ballistic annihilation

open access: yes, 2006
Using event-driven molecular dynamics we study one- and two-dimensional ballistic annihilation. We estimate exponents $\xi$ and $\gamma$ that describe the long-time decay of the number of particles ($n(t)\sim t^{-\xi}$) and of their typical velocity ($v ...
Adam Lipowski   +4 more
core   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Hydrodynamic model for picosecond propagation of laser-created nanoplasmas

open access: yes, 2015
The interaction of a free-electron-laser pulse with a moderate or large size cluster is known to create a quasi-neutral nanoplasma, which then expands on hydrodynamic timescale, i.e., $>1$ ps.
Jurek, Zoltan   +3 more
core   +1 more source

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