Results 81 to 90 of about 3,395,940 (292)

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

The Mesolithic–Neolithic transition in the Iron Gates, Southeast Europe:Calibration and dietary issues [PDF]

, 2009
This paper discusses an aquatic reservoir effect present in Mesolithic human bone samples from the Iron Gates section of the River Danube. Its magnitude has been calculated from a comparison of the 14C ages of human bones and terrestrial mammal bones ...
McSweeney, Kathleen, Bartosiewicz, Laszlo, Pickard, Catriona, Bonsall, Clive, Boroneanț, Adina, Cook, Gordon T.   +5 more
core  

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Molecular Logic Gates Based on Ferrocene-Containing Compounds

Inorganics
Ferrocene has a unique structure, i.e., a central iron atom neatly sandwiched between two cyclopentadienyl rings, which has revolutionized the chemists’ views about how metals bind to organic π-systems.
Christina Eleftheria Tzeliou, Konstantinos P. Zois, Demeter Tzeli   +2 more
doaj   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

FEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn, Artur Osyczka, Marcin Sarewicz   +2 more
wiley   +1 more source

Wide range zero-thermal-quenching ultralong phosphorescence from zero-dimensional metal halide hybrids

Nature Communications, 2020
Molecular luminescence is generally significantly quenched at high temperature. Here the authors report a zero-dimensional metal halide hybrid that exhibits zero-thermal-quenching ultralong phosphorescence over a wide temperature range of 220 K, and ...
Shuya Liu, Xiaoyu Fang, Bo Lu, Dongpeng Yan   +3 more
doaj   +1 more source

In vitro generation of regulatory T cells: A challenging tool for studying immune aging in humans

FEBS Open Bio, EarlyView.
In vitro induction of human regulatory T cells using standard protocols generates suppressive, Foxp3‐expressing CD4+ T cells independently of TGF‐β supplementation and donor age. Regulatory T (Treg) cells play a key role in immune tolerance and homeostasis.
Lynn Muller, Jana Bleher, Birgit Weinberger, Lourdes Rocamora‐Reverte   +3 more
wiley   +1 more source

Architecture of Molecular Logic Gates: From Design to Application as Optical Detection Devices

Organics
Three decades after A. P. de Silva’s seminal paper introduced the concept of logic gates at the molecular level, the field of molecular logic gates (MLGs) has witnessed significant advancements.
Gleiston G. Dias, Francielly T. Souto
doaj   +1 more source

Physical Insights into Molecular Sensors, Molecular Logic Gates, and Photosensitizers in Photodynamic Therapy

Journal of Chemistry, 2019
In this article, the importance of charge/electron transfer in two rapidly growing areas of science is highlighted. In the field of molecular sensors, it plays a considerable role on the detection of molecular systems to serve as fluorescence sensors ...
Demeter Tzeli, Ioannis D. Petsalakis
doaj   +1 more source