Results 101 to 110 of about 4,217,992 (292)

Optimizing GNN Architectures Through Nonlinear Activation Functions for Potent Molecular Property Prediction

Computation
Accurate predictions of molecular properties are crucial for advancements in drug discovery and materials science. However, this task is complex and requires effective representations of molecular structures.
Areen Rasool, Jamshaid Ul Rahman, Quaid Iqbal   +2 more
doaj   +1 more source

M-Polynomials and Degree-Based Topological Indices of VC₅C₇[p,q] and HC₅C₇[p,q] Nanotubes

IEEE Access, 2019
Analysts are creating materials, for example, a carbon nanotube-based composite created by NASA that bends when a voltage is connected. Applications incorporate the use of an electrical voltage to change the shape (transform) of airship wings and ...
Jia-Bao Liu, Muhammad Younas, Mustafa Habib, Muhammad Yousaf, Waqas Nazeer   +4 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Quantitative Structure–Property Relationship Analysis in Molecular Graphs of Some Anticancer Drugs with Temperature Indices Approach

Mathematics
The most important application of anticancer drugs in various forms (alkylating agents, hormones agents, and antimetabolites) is the treatment of malignant diseases.
Xiaolong Shi, Ruiqi Cai, Jaber Ramezani Tousi, Ali Asghar Talebi   +3 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Representing Space: A Hybrid Genetic Algorithm for Aesthetic Graph Layout [PDF]

, 1998
This paper describes a hybrid Genetic Algorithm (GA) that is used to improve the layout of a graph according to a number of aesthetic criteria.
Rodgers, Peter, Hobbs, M.H.W.
core  

The H-Line Signed Graph of a Signed Graph [PDF]

, 2010
For standard terminology and notion in graph theory we refer the reader to Harary; the non-standard will be given in this paper as and when required.
Reddy, Siva Kota, Subramanya, M.S., Rangarajan, R.   +2 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Forcing (G,D)-number of a Graph [PDF]

, 2011
By a graph G=(V,E), we mean a finite, undirected connected graph without loops and multiple ...
Nagarajan, A., A.Nagarajan, Palani, K., K.Palani   +3 more
core   +1 more source

Chemical Equitable Partitions: A New Perspective on Molecular Symmetries and Its Implications for the Study of Structure–Property Relationships

Proceedings
In this work, the concept of equitable partition is applied to molecular graphs to define quantitative descriptors of the symmetry and complexity of molecules, with the ultimate goal of shedding new light on the structure–property relationships of ...
Vasilios Raptis, Ioannis Michos
doaj   +1 more source