Results 71 to 80 of about 481,445 (263)
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
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, 2014 Citation: 'molecular graph' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.MT07069 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
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ProceedingsIn this work, the concept of equitable partition is applied to molecular graphs to define quantitative descriptors of the symmetry and complexity of molecules, with the ultimate goal of shedding new light on the structure–property relationships of ...
Vasilios Raptis, Ioannis Michos
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Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
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The Structure and Chemical Bond of FOX-7: The AIM Analysis and Vibrational Normal Modes [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 2011 FOX-7 (1,1-diamino-2,2-dinitroethylene) recently is expected as a relatively new energetic material with high-performance and low sensitivity. The RHF and MP2 levels and DFT method with B3LYP functional with aug-cc-pVDZ basis set have been used for ...
Jamshid Najafpour, Narges Zohari
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Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
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Total and Double Total Domination Number on Hexagonal Grid
Mathematics, 2019 In this paper, we determine the upper and lower bound for the total domination number and exact values and the upper bound for the double-total domination number on hexagonal grid H m , n with m hexagons in a row and n hexagons in a column ...
Antoaneta Klobučar, Ana Klobučar
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Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
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On the Scalability of GNNs for Molecular Graphs
Advances in Neural Information Processing Systems 37Scaling deep learning models has been at the heart of recent revolutions in language modelling and image generation. Practitioners have observed a strong relationship between model size, dataset size, and performance. However, structure-based architectures such as Graph Neural Networks (GNNs) are yet to show the benefits of scale mainly due to the ...
Maciej Sypetkowski +6 more
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Eccentricity-Based Topological Indices of a Cyclic Octahedron Structure
Mathematics, 2018 In this article, we study the chemical graph of a cyclic octahedron structure of dimension n and compute the eccentric connectivity polynomial, the eccentric connectivity index, the total eccentricity, the average eccentricity, the first Zagreb index ...
Manzoor Ahmed Zahid +3 more
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