Results 71 to 80 of about 446,524 (307)
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Main Group Metal ChemistryTopological indices play a central role in mathematical chemistry for correlating structural features of molecular graphs with physicochemical properties.
Noreen Tahira, Salman Muhammad
doaj +1 more source
Total and Double Total Domination Number on Hexagonal Grid
Mathematics, 2019 In this paper, we determine the upper and lower bound for the total domination number and exact values and the upper bound for the double-total domination number on hexagonal grid H m , n with m hexagons in a row and n hexagons in a column ...
Antoaneta Klobučar, Ana Klobučar
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Eccentricity-Based Topological Indices of a Cyclic Octahedron Structure
Mathematics, 2018 In this article, we study the chemical graph of a cyclic octahedron structure of dimension n and compute the eccentric connectivity polynomial, the eccentric connectivity index, the total eccentricity, the average eccentricity, the first Zagreb index ...
Manzoor Ahmed Zahid +3 more
doaj +1 more source
Combined Molecular Graph Neural Network and Structural Docking Selects Potent Programmable Cell Death Protein 1/Programmable Death-Ligand 1 (PD-1/PD-L1) Small Molecule Inhibitors [PDF]
, 2020 Prageeth R. Wijewardhane +3 more
openalex +1 more source
Graph Residual Flow for Molecular Graph Generation
, 2019 Statistical generative models for molecular graphs attract attention from many researchers from the fields of bio- and chemo-informatics. Among these models, invertible flow-based approaches are not fully explored yet. In this paper, we propose a powerful invertible flow for molecular graphs, called graph residual flow (GRF).
Honda, Shion +4 more
openaire +2 more sources
More hyperenergetic molecular graphs
Journal of the Serbian Chemical Society, 2000 If G is a molecular graph and ?1,?2,... ?n are its eigenvalues, then the energy of G is equal to E(G) = |?1|+|?2|+ ... +|?n|. This energy cannot exceed the value n?n-1 ? n3/2. The graph G is said to be hyperenergetic if E(G)>2n-2. We describe the construc?tion of hyperenergetic graphs G for which E(G)?1/2 n3/2.
Koolen, Jack H. +3 more
openaire +3 more sources
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Valency-based molecular descriptors of Bakelite network BNmn$B\text N_{m}^{n}$
Open Chemistry, 2019 Bakelite network BNmn$BN_{m}^{n}$is a molecular graph of bakelite, a pioneering and revolutionary synthetic polymer (Thermosetting Plastic) and regarded as the material of a thousand uses. In this paper, we aim to compute various degree-based topological
Ahmad Maqsood +3 more
doaj +1 more source