Results 171 to 180 of about 1,886,243 (328)

Imaging Spectrometric Observatory (ISO) [PDF]

The imaging spectrometric observatory (ISO) is discussed. The objectives of this instrument are to measure the spectral signatures of a large range of minor constituents, metastable, and excited species of both atomic and molecular ions, and neutrals in ...
Roberts, W. T.
core   +1 more source

Mapping Molecular Interactions and Transport in Cell Membranes by Image Correlation Spectroscopy

, 2005
Eleonora Keating, Claire M. Brown, Nils O. Petersen   +2 more
openalex   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Molecular imaging concepts [PDF]

Journal of Nuclear Cardiology, 2016
Jakub, Toczek, Mehran M, Sadeghi
openaire   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Ex6R15C2 PSD95-1 from Synaptic molecular imaging in spared and deprived columns of mouse barrel cortex with array tomography.

, 2014
Collins Weiler Nicholas, Forrest Collman, T Vogelstein Joshua, Randal Burns, J Smith Stephen   +4 more
openalex   +1 more source

Multiplexed molecular imaging with surface enhanced resonance Raman scattering nanoprobes reveals immunotherapy response in mice via multichannel image segmentation [PDF]

, 2022
Chrysafis Andreou, Konstantinos Plakas, Naxhije Berisha, Mathieu Gigoux, Lauren E. Rosch, Rustin Mirsafavi, Anton Oseledchyk, Suchetan Pal, Dmitriy Zamarin, Taha Merghoub, Michael R. Detty, Moritz F. Kircher   +11 more
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Ultrafast molecular orbital imaging based on attosecond photoelectron diffraction

, 2015
Yang Li, Meiyan Qin, Xiaosong Zhu, Qingbin Zhang, Pengfei Lan, Peixiang Lu   +5 more
openalex   +1 more source

Molecular imaging for cancer immunotherapy [PDF]

, 2023
Jing Yu, Bo Gao
openalex   +1 more source