Results 51 to 60 of about 541,631 (349)

Density functional theory in transition-metal chemistry: a self-consistent Hubbard U approach

, 2006
Transition-metal centers are the active sites for many biological and inorganic chemical reactions. Notwithstanding this central importance, density-functional theory calculations based on generalized-gradient approximations often fail to describe ...
C. Rovira, Damian A. Scherlis, Heather J. Kulik, Hollas, Matteo Cococcioni, Nicola Marzari   +5 more
core   +1 more source

Conformational Dynamics of metallo-β-lactamase CcrA during Catalysis Investigated by Using DEER Spectroscopy [PDF]

, 2015
Previous crystallographic and mutagenesis studies have implicated the role of a position-conserved hairpin loop in the metallo-β-lactamases in substrate binding and catalysis.
Aitha, Mahesh, Bennett, Brian, Crowder, Michael W., Lorigan, Gary A., McCarrick, Robert, Moritz, Lindsay, Roche, Zahilyn, Sahu, Indra D., Sanyurah, Omar   +8 more
core   +2 more sources

Structural Basis of the Immunological Cross-Reactivity between Kiwi and Birch Pollen

Foods, 2023
Allergies related to kiwi consumption have become a growing health concern, with their prevalence on the rise. Many of these allergic reactions are attributed to cross-reactivity, particularly with the major allergen found in birch pollen.
Ricarda Zeindl, Annika L. Franzmann, Monica L. Fernández-Quintero, Clarissa A. Seidler, Valentin J. Hoerschinger, Klaus R. Liedl, Martin Tollinger   +6 more
doaj   +1 more source

Bioactive glass-based organic/inorganic hybrids: an analysis of the current trends in polymer design and selection.

Journal of materials chemistry. B, 2022
Bioactive glass-based organic/inorganic hybrids are a family of materials holding great promise in the biomedical field. Developed from bioactive glasses following recent advances in sol-gel and polymer chemistry, they can overcome many limitations of ...
Lukas Gritsch, Cédric Bossard, É. Jallot, Julian R. Jones, J. Lao   +4 more
semanticscholar   +1 more source

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

Nanofiller-tuned microporous polymer molecular sieves for energy and environmental processes [PDF]

, 2015
10.1039/c5ta09060aJournal of Materials Chemistry A41270 ...
Cao, S, Cheetham, AK, Pritchard, RH, Qiblawey, H, Sivaniah, E, Song, Q, Terentjev, EM   +6 more
core   +1 more source

Effect of inorganic material surface chemistry on structures and fracture behaviours of epoxy resin

Nature Communications
The mechanisms underlying the influence of the surface chemistry of inorganic materials on polymer structures and fracture behaviours near adhesive interfaces are not fully understood.
Tomohiro Miyata, Yohei K. Sato, Yoshiaki Kawagoe, K. Shirasu, Hsiao-Fang Wang, Akemi Kumagai, Sora Kinoshita, M. Mizukami, Kaname Yoshida, Hsin-Hui Huang, Tomonaga Okabe, K. Hagita, Teruyasu Mizoguchi, Hiroshi Jinnai   +13 more
semanticscholar   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Methyl Methacrylate Oligomerically-Modified Clay and its Poly (Methyl Methacrylate) Nanocomposites [PDF]

, 2005
A methyl methacrylate oligomerically-modified clay was used to prepare poly(methyl methacrylate) clay nanocomposites by melt blending and the effect of the clay loading level on the modified clay and corresponding nanocomposite was studied.
Jiang, David D., Wilkie, Charles A., Zheng, Xiaoxia   +2 more
core   +2 more sources

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

FEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani, Hiroya Ueda, Ayumi Kawata, Yuki Sato, Kotomi Inomata, Hiroshi Mano, Masahiro Wada, Kenji Kobata   +7 more
wiley   +1 more source