Results 51 to 60 of about 410,338 (315)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Behaviours of natural organic matter in membrane filtration for surface water treatment : a review [PDF]

, 2006
Membrane application in surface water treatment provides many advantages over conventional treatment. However, this effort is hampered by the fouling issue, which restricts its widespread application due to increases in hydraulic resistances, operational
Ismail, A. F., Salim, Razman, Zularisam, A. W.   +2 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Superspace crystallography: a key to the chemistry and properties

IUCrJ, 2015
An overview is given of the recent advances in the field of modulated molecular and inorganic crystals with an emphasis on the links between incommensurability, intermolecular and interatomic interactions and, wherever possible, the properties of the ...
Carlos Basílio Pinheiro, Artem M. Abakumov   +1 more
doaj   +1 more source

On the intrinsic dynamic nature of the rigid UiO-66 metal-organic framework [PDF]

, 2018
UiO-66 is a showcase example of an extremely stable metal-organic framework, which maintains its structural integrity during activation processes such as linker exchange and dehydration.
Caratelli, Chiara, De Wispelaere, Kristof, Demuynck, Ruben, Hajek, Julianna, Van Speybroeck, Veronique, Vanduyfhuys, Louis, Waroquier, Michel   +6 more
core   +2 more sources

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Conformational Dynamics of metallo-β-lactamase CcrA during Catalysis Investigated by Using DEER Spectroscopy [PDF]

, 2015
Previous crystallographic and mutagenesis studies have implicated the role of a position-conserved hairpin loop in the metallo-β-lactamases in substrate binding and catalysis.
Aitha, Mahesh, Bennett, Brian, Crowder, Michael W., Lorigan, Gary A., McCarrick, Robert, Moritz, Lindsay, Roche, Zahilyn, Sahu, Indra D., Sanyurah, Omar   +8 more
core   +2 more sources

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Surprisingly Fast Interface and Elbow Angle Dynamics of Antigen-Binding Fragments

Frontiers in Molecular Biosciences, 2020
Fab consist of a heavy and light chain and can be subdivided into a variable (VH and VL) and a constant region (CH1 and CL). The variable region contains the complementarity-determining region (CDR), which is formed by six hypervariable loops, shaping ...
Monica L. Fernández-Quintero, Katharina B. Kroell, Martin C. Heiss, Johannes R. Loeffler, Patrick K. Quoika, Franz Waibl, Alexander Bujotzek, Ekkehard Moessner, Guy Georges, Klaus R. Liedl   +9 more
doaj   +1 more source

Comparison of MRI properties between multimeric DOTAGA and DO3A gadolinium-dendron conjugates [PDF]

, 2019
The inherent lack of sensitivity of MRI needs the development of new Gd contrast agents in order to extend 20Hz,37%, the application of this technique to cellular imaging.
Boutry, Sébastien, Cadiou, Cyril, Chuburu, Françoise, De Smedt, Stefaan, Harakat, Dominique, Henoumont, Céline, Laurent, Sophie, Malytskyi, Volodymyr, Moreau, Juliette, Muller, Robert N., Ndiaye, Maleotane, Sauvage, Félix, Vangijzegem, Thomas, Wels, Mike   +13 more
core   +3 more sources