Results 11 to 20 of about 12,554,924 (329)

MolTrans: Molecular Interaction Transformer for drug–target interaction prediction [PDF]

Bioinform., 2020
Motivation Drug–target interaction (DTI) prediction is a foundational task for in-silico drug discovery, which is costly and time-consuming due to the need of experimental search over large drug compound space.
Kexin Huang, Cao Xiao, Lucas Glass, Jimeng Sun   +3 more
semanticscholar   +1 more source

Molecular interaction analysis and visualization of protein-ligand docking using Biovia Discovery Studio Visualizer

Indonesian Journal of Computational Biology (IJCB), 2023
Molecular docking interpretation is one of the crucial part before determining the result. Docking is commonly used to study the biomolecular interaction, usually for protein-ligand interaction, and to study about the molecular mechanism.
Umi Baroroh, S.Si., M.Biotek., Zahra Silmi Muscifa, Wanda Destiarani, Fauzian Giansyah Rohmatullah, Muhammad Yusuf   +4 more
semanticscholar   +1 more source

The IntAct database: efficient access to fine-grained molecular interaction data

Nucleic Acids Res., 2021
The IntAct molecular interaction database (https://www.ebi.ac.uk/intact) is a curated resource of molecular interactions, derived from the scientific literature and from direct data depositions.
N. del-Toro, A. Shrivastava, E. Ragueneau, B. Meldal, C. Combe, E. Barrera, L. Perfetto, Karyn How, Prashansa Ratan, Gautam Shirodkar, Odilia Lu, Bálint Mészáros, Xavier Watkins, Sangya Pundir, L. Licata, M. Iannuccelli, M. Pellegrini, M. Martin, S. Panni, M. Duesbury, Sylvain D. Vallet, J. Rappsilber, S. Ricard-Blum, G. Cesareni, L. Salwínski, S. Orchard, P. Porras, Kalpana Panneerselvam, H. Hermjakob   +28 more
semanticscholar   +1 more source

The Molecular Interaction of Collagen with Cell Receptors for Biological Function

Polymers, 2022
Collagen, an extracellular protein, covers the entire human body and has several important biological functions in normal physiology. Recently, collagen from non-human sources has attracted attention for therapeutic management and biomedical applications.
Jeevithan Elango, Chunyu Hou, Bin Bao, Shujun Wang, J. E. Maté Sánchez de Val, Wenhui Wu   +5 more
semanticscholar   +1 more source

Emerging landscape of molecular interaction networks: Opportunities, challenges and prospects

Journal of Biosciences, 2022
Network biology finds application in interpreting molecular interaction networks and providing insightful inferences using graph theoretical analysis of biological systems.
Gauri Panditrao, Rupa Bhowmick, C. Meena, R. Sarkar   +3 more
semanticscholar   +1 more source

CSGNN: Contrastive Self-Supervised Graph Neural Network for Molecular Interaction Prediction

International Joint Conference on Artificial Intelligence, 2021
Molecular interactions are significant resources for analyzing sophisticated biological systems. Identification of multifarious molecular interactions attracts increasing attention in biomedicine, bioinformatics, and human healthcare communities ...
Chengshuai Zhao, Shuai Liu, Feng Huang, Shichao Liu, Wen Zhang   +4 more
semanticscholar   +1 more source

IntAct App: a Cytoscape application for molecular interaction network visualization and analysis

Bioinform., 2021
Summary IntAct App is a Cytoscape 3 application that grants in-depth access to IntAct’s molecular interaction data. It build networks where nodes are interacting molecules (mainly proteins, but also genes, RNA, chemicals…) and edges represent evidence of
E. Ragueneau, A. Shrivastava, J. Morris, N. del-Toro, H. Hermjakob, P. Porras   +5 more
semanticscholar   +1 more source

Anti-inflammatory effects of recreational marijuana in virally suppressed youth with HIV-1 are reversed by use of tobacco products in combination with marijuana

Retrovirology, 2022
Background Marijuana’s putative anti-inflammatory properties may benefit HIV-associated comorbidities. How recreational marijuana use affects gene expression in peripheral blood cells (PBC) among youth with HIV-1 (YWH) is unknown.
Li Yin, Ashok R. Dinasarapu, Samiksha A. Borkar, Kai-Fen Chang, Kristina De Paris, Julie J. Kim-Chang, John W. Sleasman, Maureen M. Goodenow   +7 more
doaj   +1 more source

A Live Probiotic Vaccine Prototype Based on Conserved Influenza a Virus Antigens Protect Mice against Lethal Influenza Virus Infection

Biomedicines, 2021
Background: Due to the highly variable nature of the antigenic properties of the influenza virus, many efforts have been made to develop broadly reactive influenza vaccines. Various vaccine platforms have been explored to deliver conserved viral antigens
Daria Mezhenskaya, Irina Isakova-Sivak, Tatiana Gupalova, Elena Bormotova, Eugenia Kuleshevich, Tatiana Kramskaya, Galina Leontieva, Larisa Rudenko, Alexander Suvorov   +8 more
doaj   +1 more source

Induced Local and Systemic Defense Responses in Tomato Underlying Interactions Between the Root-Knot Nematode Meloidogyne incognita and the Potato Aphid Macrosiphum euphorbiae

Frontiers in Plant Science, 2021
Plants mediate interactions between different herbivores that attack simultaneously or sequentially aboveground (AG) and belowground (BG) organs. The local and systemic activation of hormonal signaling pathways and the concomitant accumulation of defense
Crispus M. Mbaluto, Crispus M. Mbaluto, Esraa M. Ahmad, Anne Mädicke, Anne Mädicke, Katharina Grosser, Katharina Grosser, Nicole M. van Dam, Nicole M. van Dam, Ainhoa Martínez-Medina   +9 more
doaj   +1 more source