Results 31 to 40 of about 1,862,376 (267)

Defining host–pathogen interactions employing an artificial intelligence workflow

eLife, 2019
For image-based infection biology, accurate unbiased quantification of host–pathogen interactions is essential, yet often performed manually or using limited enumeration employing simple image analysis algorithms based on image segmentation. Host protein
Daniel Fisch, Artur Yakimovich, Barbara Clough, Joseph Wright, Monique Bunyan, Michael Howell, Jason Mercer, Eva Frickel   +7 more
doaj   +1 more source

Experimental and Computational Evaluation of 1,2,4-Triazolium-Based Ionic Liquids for Carbon Dioxide Capture

Separations, 2023
Utilization of ionic liquids (ILs) for carbon dioxide (CO2) capture is continuously growing, and further understanding of the factors that influence its solubility (notably for new ILs) is crucial. Herein, CO2 absorption of two 1,2,4-triazolium-based ILs
Sulafa Abdalmageed Saadaldeen Mohammed, Wan Zaireen Nisa Yahya, Mohamad Azmi Bustam, Md Golam Kibria   +3 more
doaj   +1 more source

Shape Complementarity Optimization of Antibody–Antigen Interfaces: The Application to SARS-CoV-2 Spike Protein

Frontiers in Molecular Biosciences, 2022
Many factors influence biomolecule binding, and its assessment constitutes an elusive challenge in computational structural biology. In this aspect, the evaluation of shape complementarity at molecular interfaces is one of the main factors to be ...
Alfredo De Lauro, Lorenzo Di Rienzo, Mattia Miotto, Pier Paolo Olimpieri, Edoardo Milanetti, Edoardo Milanetti, Giancarlo Ruocco, Giancarlo Ruocco   +7 more
doaj   +1 more source

An NMR Study on Hydration and Molecular Interaction of Phytantriol-Based Liquid Crystals

Pharmaceutics, 2022
Phytantriol-based lyotropic liquid crystals (LLCs) have emerged as a new nanodrug delivery system. However, the understanding of phytantriol-based LLCs is lacking. In this study, we use NMR technology to characterize LLC formation over two months.
Yu Lu, Di Zhu, Quynh Le, Yuji Wang, Wei Wang   +4 more
doaj   +1 more source

Fluorination Enables Tunable Molecular Interaction and Photovoltaic Performance in Non-Fullerene Solar Cells Based on Ester-Substituted Polythiophene

Frontiers in Chemistry, 2021
Owing to the advantages of low synthetic cost and high scalability of synthesis, polythiophene and its derivatives (PTs) have been of interest in the community of organic photovoltaics (OPVs). Nevertheless, the typical efficiency of PT based photovoltaic
Ziqi Liang, Mengyuan Gao, Bo Zhang, Junjiang Wu, Zhongxiang Peng, Miaomiao Li, Miaomiao Li, Long Ye, Long Ye, Yanhou Geng, Yanhou Geng, Yanhou Geng   +11 more
doaj   +1 more source

Topology of molecular interaction networks [PDF]

BMC Systems Biology, 2013
Molecular interactions are often represented as network models which have become the common language of many areas of biology. Graphs serve as convenient mathematical representations of network models and have themselves become objects of study. Their topology has been intensively researched over the last decade after evidence was found that they share
Winterbach, W. (author), Van Mieghem, P. (author), Reinders, M. (author), Wang, H. (author), De Ridder, D. (author)   +4 more
openaire   +4 more sources

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro, Freda Qi, Karen Colwill, Alina D. Dorogy, Ying Liu, Michelle Science, Anne‐Claude Gingras, James M. Rini, Sumit Gupta, Sarah Alexander, Shelly Bolotin, Tania H. Watts   +11 more
wiley   +1 more source

High-throughput workflow for cultivation and characterization of gut microbiota strains with anti-inflammatory properties and metabolite signature associated with gut-brain communication

Scientific Reports
The gut microbiota is deeply interconnected with the brain, a phenomenon often referred to as the gut-brain axis. Dysfunction in the microbiota-gut-brain axis can cause various neurological and psychiatric disorders associated with chronic inflammation ...
Jelena Đokić, Miroslav Dinić, Svetlana Soković Bajić, Aleksandar Bisenić, Hristina Mitrović, Stefan Jakovljević, Dušan Radojević, Emilija Brdarić, Jovanka Lukić, Milica Živković, Maja Tolinački, Amarela Terzić-Vidojević, Nataša Golić   +12 more
doaj   +1 more source

Molecular basis for cellular retinoic acid-binding protein 1 in modulating CaMKII activation

Frontiers in Molecular Biosciences, 2023
Introduction: Cellular retinoic acid (RA)-binding protein 1 (CRABP1) is a highly conserved protein comprised of an anti-parallel, beta-barrel, and a helix-turn-helix segment outside this barrel.
Jennifer Nhieu, Michelle C. Miller, Thomas A. Lerdall, Kevin H. Mayo, Li-Na Wei   +4 more
doaj   +1 more source

Molecular Interactions in the Assembly of Coronaviruses

, 2005
This chapter describes the interactions between the different structural components of the viruses and discusses their relevance for the process of virion formation. Two key factors determine the efficiency of the assembly process: intracellular transport and molecular interactions. Many viruses have evolved elaborate strategies to ensure the swift and
de Haan, C.A.M., Rottier, P.J.M.
openaire   +3 more sources