Results 51 to 60 of about 1,862,376 (267)

Challenges of polymer electrolyte with wide electrochemical window for high energy solid‐state lithium batteries

InfoMat, 2023
With the rapid development of energy storage technology, solid‐state lithium batteries with high energy density, power density, and safety are considered as the ideal choice for the next generation of energy storage devices.
Sida Huo, Li Sheng, Wendong Xue, Li Wang, Hong Xu, Hao Zhang, Xiangming He   +6 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Insight into immunoregulatory and neuromodulatory capability of Bacteroides cellulosilyticus and Bacteroides xylanisolvens human gut microbiota isolates

Scientific Reports
Alterations in the abundance of Bacteroides species are linked to the disruption of the intestinal epithelial barrier and chronic inflammation and has been increasingly recognized as a factor in the development of neurological and neuropsychiatric ...
Miroslav Dinić, Jelena Đokić, Stefan Jakovljević, Emilija Brdarić, Hristina Mitrović, Aleksandar Bisenić, Dušan Radojević, Svetlana Soković Bajić, Sergej Tomić, Nataša Golić   +9 more
doaj   +1 more source

Plasmid-like dynamics of persistent RNA viruses in the host fungal population

Journal of Virology
Unlike the well-known acute or chronic animal and plant RNA viruses, most fungal RNA viruses (RNA mycoviruses) have a persistent life cycle. They lack an extracellular infection route and coexist with their hosts for a lifetime.
Yuto Chiba, Seiyo Watanabe, Ayano Ikeda, Shuhei Miyashita, Daisuke Hagiwara, Syun-ichi Urayama   +5 more
doaj   +1 more source

A Toolbox for Site-Specific Labeling of RecQ Helicase With a Single Fluorophore Used in the Single-Molecule Assay

Frontiers in Molecular Biosciences, 2020
Fluorescently labeled proteins can improve the detection sensitivity and have been widely used in a variety of biological measurements. In single-molecule assays, site-specific labeling of proteins enables the visualization of molecular interactions ...
Fang-Yuan Teng, Fang-Yuan Teng, Fang-Yuan Teng, Fang-Yuan Teng, Zong-Zhe Jiang, Zong-Zhe Jiang, Ling-Yun Huang, Man Guo, Feng Chen, Xi-Miao Hou, Xu-Guang Xi, Xu-Guang Xi, Yong Xu, Yong Xu   +13 more
doaj   +1 more source

Two Novel Lytic Bacteriophages Infecting Enterococcus spp. Are Promising Candidates for Targeted Antibacterial Therapy

Viruses, 2022
The rapid emergence of antibiotic resistance is of major concern globally. Among the most worrying pathogenic bacteria are vancomycin-resistant enterococci. Phage therapy is a highly promising method for controlling enterococcal infections. In this study,
Pavel V. Tkachev, Ivan M. Pchelin, Daniil V. Azarov, Andrey N. Gorshkov, Olga V. Shamova, Alexander V. Dmitriev, Artemiy E. Goncharov   +6 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Insights into T cell recognition of antigen: Significance of two-dimensional kinetic parameters

Frontiers in Immunology, 2012
The kinetic parameters governing T cell activation have been intensely studied for over a decade. However, the details of how the various aspects of receptor:ligand interactions culminate in T cell activation remains shrouded in mystery.
Lindsay J Edwards, Veronika I Zarnitsyna, Jennifer D Hood, Brian eEvavold, Cheng eZhu   +4 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source